Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 4/20 | 0.55 |
| ▸ | CA9 | Q16790 | 4/20 | 0.55 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA3 | P07451 | 1/20 | 0.47 |
| ▸ | CA4 | P22748 | 1/20 | 0.47 |
| ▸ | CA6 | P23280 | 1/20 | 0.47 |
| ▸ | CA5A | P35218 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.47 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.46 |
| ▸ | FEN1 | P39748 | 1/20 | 0.44 |
| ▸ | CDK4 | P11802 | 3/20 | 0.43 |
| ▸ | CCND1 | P24385 | 3/20 | 0.43 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16635074 | 0.88 | CA12 (0.50) | CA12CA9CA1CA3CA4 | |
| SCHEMBL16135235 | 0.84 | PDE3B (0.50) | CA12CA9CA1CA3CA4 | |
| SCHEMBL2324532 | 0.84 | CA12 (0.59) | CA12CA9CA1CA3CA4 | |
| SCHEMBL17980649 | 0.80 | MAP2K1 (0.54) | CA12CA9KDM4EFEN1PDE10A | |
| SCHEMBL29350379 | 0.80 | CA12 (0.43) | CA12CA9CA1CA3CA4 | |
| SCHEMBL17165602 | 0.80 | CA12 (0.43) | CA12CA9CA1CA3CA4 | |
| SCHEMBL2116388 | 0.80 | CA12 (0.53) | CA12CA9CA1CA3CA4 | |
| SCHEMBL19751532 | 0.76 | KDM4E (0.49) | CA12CA9CA1CA3CA4 | |
| SCHEMBL1994599 | 0.75 | DPP4 (0.42) | CA12CA9CA1CA3CA4 | |
| SCHEMBL31634734 | 0.75 | GSTP1 (0.47) | CA12CA9CA1CA3CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108503582-B | Microwave-assisted synthesis method of 2- (1H) -quinolinone compounds | 湖南科技学院 | 2020-01-07 | — | — | CN | disclosed |
| CN-108503582-A | The microwave assisted synthesizing method of 2- (1H)-quinolinones compound | 湖南科技学院 | 2018-09-07 | — | — | CN | disclosed |