Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 4/20 | 0.46 |
| ▸ | HTR2A | P28223 | 4/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.44 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 2/20 | 0.36 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4672668 | 0.83 | HRH1 (0.62) | HRH1HTR2ATAAR1DPP4LOXL2 | |
| SCHEMBL22620835 | 0.83 | HRH1 (0.62) | HRH1HTR2ATAAR1DPP4LOXL2 | |
| SCHEMBL5189954 | 0.83 | HRH1 (0.62) | HRH1HTR2ATAAR1DPP4LOXL2 | |
| SCHEMBL28918758 | 0.82 | HRH1 (0.42) | HRH1HTR2ATAAR1 | |
| Hydrochloric Acid SCHEMBL7970943 | 0.81 | HRH1 (0.60) | HRH1HTR2ATAAR1CHRNB2CHRNA4 | |
| SCHEMBL1538461 | 0.79 | TAAR1 (0.42) | HRH1HTR2ATAAR1DPP4F2 | |
| SCHEMBL13715342 | 0.79 | HRH1 (0.64) | HRH1HTR2ATAAR1CHRNB2CHRNA4 | |
| SCHEMBL14767588 | 0.78 | AOC3 (0.46) | HRH1HTR2ATAAR1 | |
| SCHEMBL16645107 | 0.78 | HRH1 (0.39) | HRH1HTR2ATAAR1DPP4F2 | |
| SCHEMBL4890479 | 0.78 | HRH1 (0.39) | HRH1HTR2ATAAR1DPP4F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108602824-A | It is a kind of adjust kinases compound tosilate and its crystallization | 正大天晴药业集团股份有限公司 | 2018-09-28 | — | — | CN | disclosed |