Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.58 |
| ▸ | MAPT | P10636 | 5/20 | 0.58 |
| ▸ | HSP90AA1 | P07900 | 4/20 | 0.57 |
| ▸ | CCR6 | P51684 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 3/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.54 |
| ▸ | CA9 | Q16790 | 1/20 | 0.54 |
| ▸ | MGAM | O43451 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | SI | P14410 | 1/20 | 0.53 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | MITF | O75030 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28244680 | 1.00 | MAOB (0.58) | MAOBMAPTHSP90AA1CCR6POLB | |
| SCHEMBL3024329 | 0.89 | MGAM (0.64) | MAOBMAPTHSP90AA1POLBMGAM | |
| SCHEMBL3024334 | 0.89 | MGAM (0.64) | MAOBMAPTHSP90AA1POLBMGAM | |
| SCHEMBL4382686 | 0.87 | HSP90AA1 (0.53) | MAOBMAPTHSP90AA1CCR6POLB | |
| SCHEMBL4382687 | 0.87 | HSP90AA1 (0.53) | MAOBMAPTHSP90AA1CCR6POLB | |
| SCHEMBL28244685 | 0.83 | MAOB (0.68) | MAOBNPSR1KDM4ECA12CA9 | |
| SCHEMBL28244683 | 0.83 | MAOB (0.68) | MAOBNPSR1KDM4ECA12CA9 | |
| SCHEMBL4515467 | 0.82 | MAOB (0.68) | MAOBKDM4ECA12CA9MGAM | |
| SCHEMBL4515465 | 0.82 | MAOB (0.68) | MAOBKDM4ECA12CA9MGAM | |
| SCHEMBL28458506 | 0.81 | MGAM (0.62) | MAOBMAPTKDM4ECA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108558807-A | The method of one pot process cumarin base chalcone compounds | 河南中烟工业有限责任公司 | 2018-09-21 | — | — | CN | disclosed |