Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 5/20 | 0.62 |
| ▸ | PLG | P00747 | 2/20 | 0.62 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.57 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.56 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.56 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.56 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.54 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.54 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.54 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.54 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.54 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.51 |
| ▸ | PIM1 | P11309 | 1/20 | 0.51 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.51 |
| ▸ | APP | P05067 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30888879 | 0.88 | PLAU (0.57) | PLAUPLGHDAC8HDAC6HDAC1 | |
| SCHEMBL15971036 | 0.88 | PLAU (0.57) | PLAUPLGHDAC8HDAC6HDAC1 | |
| SCHEMBL15612932 | 0.87 | HDAC6 (0.58) | PLAUPLGHDAC8HDAC6HDAC1 | |
| SCHEMBL7877701 | 0.85 | PLAU (0.55) | PLAUPLGGLO1HDAC8HDAC6 | |
| SCHEMBL12472875 | 0.85 | PLAU (0.74) | PLAUPLGHDAC8HDAC6HDAC1 | |
| SCHEMBL7706207 | 0.85 | PLAU (0.54) | PLAUPLGHDAC8HDAC6HDAC1 | |
| Hydrochloric Acid SCHEMBL7881857 | 0.84 | PLAU (0.54) | PLAUPLGGLO1HDAC8HDAC6 | |
| SCHEMBL221369 | 0.84 | PLAU (0.60) | PLAUPLGHDAC8HDAC6HDAC1 | |
| SCHEMBL30067019 | 0.84 | PLAU (0.60) | PLAUPLGHDAC8HDAC6HDAC1 | |
| SCHEMBL27248488 | 0.84 | PLAU (0.60) | PLAUPLGHDAC8HDAC6HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108699035-A | Noval chemical compound | 特殊治疗有限公司 | 2018-10-23 | — | — | CN | disclosed |