Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2824809 | 1.00 | NOTUM (0.66) | NOTUMACE | |
| SCHEMBL31207052 | 1.00 | NOTUM (0.66) | NOTUMACE | |
| SCHEMBL30745240 | 1.00 | NOTUM (0.66) | NOTUMACE | |
| SCHEMBL2830596 | 1.00 | NOTUM (0.66) | NOTUMACE | |
| SCHEMBL29697839 | 1.00 | NOTUM (0.66) | NOTUMACE | |
| SCHEMBL2827480 | 0.98 | NOTUM (0.64) | NOTUMACE | |
| SCHEMBL2827485 | 0.98 | NOTUM (0.64) | NOTUMACE | |
| SCHEMBL2827489 | 0.98 | NOTUM (0.64) | NOTUMACE | |
| SCHEMBL16350248 | 0.88 | NOTUM (0.68) | NOTUMACE | |
| SCHEMBL4707127 | 0.88 | NOTUM (0.68) | NOTUMACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117510393-A | Synthesis method of (R) -1-acetylindoline-2-carboxylic acid | 上海吉奉生物科技有限公司 | 2024-02-06 | — | — | CN | claimed |
| CN-112375028-A | Method for synthesizing (2S) -indoline-formic acid | 安徽美诺华药物化学有限公司 | 2021-02-19 | — | — | CN | claimed |
| WO-2006053440-A1 | NEW PROCESSES FOR THE PREPARATION OF OPTICALLY PURE INDOLINE-2-CARBOXYLIC ACID AND N-ACETYL-INDOLINE-2-CARBOXYLIC ACID | APOTEX PHARMACHEM INC. (CA) | 2006-05-26 | — | — | WO | claimed |
| US-6121460-A | Process for the preparation of an optically active indoline-2-carboxylic acid or derivative thereof | DSM N.V. (NL) | 2000-09-19 | — | — | US | claimed |
| EP-0937714-A1 | Process for the preparation of an optically active indoline-2-carboxylic acid or derivative thereof | DSM N.V. (NL) | 1999-08-25 | — | — | EP | claimed |
| EP-0171616-B1 | THE USE OF ALPHA-AMINO-EPSILON-CAPROLACTAM AS A RESOLVING AGENT FOR N-ACETYLINDOLINE-2-CARBOXYLIC ACID AND METHOD FOR PREPARING OPTICALLY ACTIVE N-ACETYLINDOLINE-2-CARBOXYLIC ACID | TORAY INDUSTRIES, INC. (JP) | 1989-07-12 | — | — | EP | claimed |
| US-4824964-A | Method for preparing optically active N-acetylindoline-2-carboxylic acid | TORAY INDUSTRIES, INC. (JP) | 1989-04-25 | — | — | US | claimed |
| EP-0171616-A1 | The use of alpha-amino-epsilon-caprolactam as a resolving agent for N-acetylindoline-2-carboxylic acid and method for preparing optically active N-acetylindoline-2-carboxylic acid | TORAY INDUSTRIES, INC. (JP) | 1986-02-19 | — | — | EP | claimed |
| JP-61024573-A | — | — | None | — | — | JP | disclosed |
| JP-61030572-A | — | — | None | — | — | JP | disclosed |
| JP-61024565-A | — | — | None | — | — | JP | disclosed |
| JP-61083159-A | — | — | None | — | — | JP | disclosed |
| CN-117510393-A | Synthesis method of (R) -1-acetylindoline-2-carboxylic acid | 上海吉奉生物科技有限公司 | 2024-02-06 | — | — | CN | disclosed |
| CN-117510393-A | Synthesis method of (R) -1-acetylindoline-2-carboxylic acid | 上海吉奉生物科技有限公司 | 2024-02-06 | — | — | CN | disclosed |
| JP-S6124565-A | PREPARATION OF OPTICALLY ACTIVE INDOLINE-2-CARBOXYLIC ACID | TORAY IND INC | 1986-02-03 | — | — | JP | disclosed |
| US-4479963-A | HYPOTENSIVE AGENTS | CIBA-GEIGY CORPORATION (US) | 1984-10-30 | — | — | US | disclosed |
| EP-0105919-A1 | 1-CARBOXYALKANOYLPERHYDROINDOLE-2-CARBOXYLIC ACIDS AND DERIVATIVES. | CIBA GEIGY AG (CH) | 1984-04-25 | — | — | EP | disclosed |
| WO-1983003828-A1 | 1-CARBOXYALKANOYLPERHYDROINDOLE-2-CARBOXYLIC ACIDS AND DERIVATIVES | CIBA-GEIGY AG (CH) | 1983-11-10 | — | — | WO | disclosed |
| US-4374847-A | HYPOTENSIVE AGENTS | CIBA-GEIGY CORPORATION (US) | 1983-02-22 | — | — | US | disclosed |
| EP-0051301-A1 | 1-Carboxy-azaalkyl-indolin-2-carboxylic acids, process for preparing them, pharmaceutical compositions containing them and their therapeutical use | CIBA-GEIGY AG (CH) | 1982-05-12 | — | — | EP | disclosed |