Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 8/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.36 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.35 |
| ▸ | RAD52 | P43351 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL28187197 | 1.00 | TSHR (0.51) | TSHRHPGDALDH1A1CYP3A4HCAR2 | |
| Bromide SCHEMBL28109247 | 0.89 | TSHR (0.49) | TSHRHPGDALDH1A1CYP3A4HCAR2 | |
| SCHEMBL28057251 | 0.85 | TSHR (0.53) | TSHRHPGDALDH1A1CYP3A4HCAR2 | |
| Hydrochloric Acid SCHEMBL28912715 | 0.80 | TSHR (0.47) | TSHRHPGDALDH1A1CYP3A4MAPT | |
| Bromide SCHEMBL27719168 | 0.80 | TSHR (0.53) | TSHRHPGDALDH1A1CYP3A4HCAR2 | |
| Bromide SCHEMBL28635420 | 0.79 | TSHR (0.59) | TSHRHPGDALDH1A1CYP3A4HCAR2 | |
| Bromide SCHEMBL8196037 | 0.79 | TSHR (0.59) | TSHRHPGDALDH1A1CYP3A4HCAR2 | |
| Bromide SCHEMBL29140475 | 0.79 | TSHR (0.59) | TSHRHPGDALDH1A1CYP3A4HCAR2 | |
| Bromide SCHEMBL29140477 | 0.79 | TSHR (0.59) | TSHRHPGDALDH1A1CYP3A4HCAR2 | |
| Bromide SCHEMBL28633922 | 0.79 | TSHR (0.59) | TSHRHPGDALDH1A1CYP3A4HCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108546315-B | Amphiphilic polymer oil displacement agent and preparation method and application thereof | 中国海洋石油集团有限公司 | 2020-05-12 | — | — | CN | claimed |
| CN-108715757-A | A kind of preparation method of acidproof thickening agent and its application in multifunctional acid and acid-resistant pressing crack liquid | 成都劳恩普斯科技有限公司 | 2018-10-30 | — | — | CN | claimed |
| CN-108530645-B | Amphiphilic dendritic unsaturated monomer and preparation method and application thereof | 中国海洋石油集团有限公司 | 2021-02-19 | — | — | CN | disclosed |
| CN-108546315-B | Amphiphilic polymer oil displacement agent and preparation method and application thereof | 中国海洋石油集团有限公司 | 2020-05-12 | — | — | CN | disclosed |
| CN-108546315-B | Amphiphilic polymer oil displacement agent and preparation method and application thereof | 中国海洋石油集团有限公司 | 2020-05-12 | — | — | CN | disclosed |