Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 11/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Alcohol SCHEMBL28252003 | 0.91 | GAA (0.49) | GAAKMT2ASMN1; SMN2MAPTKDM4E | |
| SCHEMBL4507226 | 0.79 | — | — | |
| SCHEMBL18703866 | 0.77 | — | — | |
| SCHEMBL4507221 | 0.75 | — | — | |
| SCHEMBL4935890 | 0.73 | — | — | |
| SCHEMBL27811434 | 0.71 | — | — | |
| SCHEMBL11765049 | 0.71 | — | — | |
| Hydrochloric Acid SCHEMBL29184275 | 0.71 | — | — | |
| SCHEMBL9547521 | 0.70 | SMN1; SMN2 (0.56) | GAAKMT2ASMN1; SMN2ALDH1A1KDM4C | |
| SCHEMBL3483318 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106699656-B | Pefloxacin aldehyde contracting 4- arylamino thiourea derivatives and its preparation method and application | 郑州工业应用技术学院 | 2019-09-24 | — | — | CN | disclosed |
| CN-106699654-B | N- methyl Ciprofloxacin aldehyde contracting 4- arylamino thiourea derivatives and its preparation method and application | 郑州工业应用技术学院 | 2019-09-24 | — | — | CN | disclosed |
| CN-106699655-B | N- methyl Lomefloxacin aldehyde contracting 4- arylamino thiourea derivatives and its preparation method and application | 郑州工业应用技术学院 | 2019-09-24 | — | — | CN | disclosed |
| CN-106674104-B | Fleraxacin aldehyde contracting 4- arylamino thiourea derivatives and its preparation method and application | 郑州工业应用技术学院 | 2019-05-31 | — | — | CN | disclosed |
| CN-106674193-B | N- methyl gatifloxacin aldehyde contracting 4- arylamino thiourea derivatives and its preparation method and application | 郑州工业应用技术学院 | 2019-03-05 | — | — | CN | disclosed |
| CN-106854214-B | Ofloxacin aldehyde contracting 4- arylamino thiourea derivatives and its preparation method and application | 郑州工业应用技术学院 | 2018-11-23 | — | — | CN | disclosed |
| CN-106854213-B | Lavo-ofloxacin aldehyde contracting 4- arylamino thiourea derivatives and its preparation method and application | 郑州工业应用技术学院 | 2018-11-23 | — | — | CN | disclosed |
| CN-106854206-B | N- methyl Moxifloxacin aldehyde contracting 4- arylamino thiourea derivatives and its preparation method and application | 郑州工业应用技术学院 | 2018-10-12 | — | — | CN | disclosed |
| CN-106674220-B | N- methyl Enoxacin aldehyde contracting 4- arylamino thiourea derivatives and its preparation method and application | 郑州工业应用技术学院 | 2018-10-09 | — | — | CN | disclosed |
| CN-106854206-A | N methyl MOXIFLOXACINs aldehyde 4 arylamino thiourea derivatives of contracting and its preparation method and application | 郑州工业应用技术学院 | 2017-06-16 | — | — | CN | disclosed |
| CN-106854214-A | Ofloxacin aldehyde 4 arylamino thiourea derivatives of contracting and its preparation method and application | 郑州工业应用技术学院 | 2017-06-16 | — | — | CN | disclosed |
| CN-106854213-A | Lavo-ofloxacin aldehyde 4 arylamino thiourea derivatives of contracting and its preparation method and application | 郑州工业应用技术学院 | 2017-06-16 | — | — | CN | disclosed |
| CN-106699655-A | N-methyl lomefloxacin acetal 4-aryl thiosemicarbazide derivative as well as preparation method and application thereof | 郑州工业应用技术学院 | 2017-05-24 | — | — | CN | disclosed |
| CN-106699654-A | N-methyl ciprofloxacin aldolase 4-aryl thiosemicarbazide derivative and preparation method and application thereof | 郑州工业应用技术学院 | 2017-05-24 | — | — | CN | disclosed |
| CN-106699779-A | Rufloxacin aldolase 4-aryl thiosemicarbazides derivative and preparation method and application thereof | 郑州工业应用技术学院 | 2017-05-24 | — | — | CN | disclosed |
| CN-106699656-A | Pefloxacin aldolase 4-aryl thiosemicarbazides derivative and preparation method and application thereof | 郑州工业应用技术学院 | 2017-05-24 | — | — | CN | disclosed |
| CN-106674193-A | N-methyl gatifloxacin acetal 4-aryl thiosemicarbazide derivative, and preparation method and application thereof | 郑州工业应用技术学院 | 2017-05-17 | — | — | CN | disclosed |
| CN-106674104-A | Fleroxacinaldehyde-4-aryl thiosemicarbazide derivative, as well as preparation method and application thereof | 郑州工业应用技术学院 | 2017-05-17 | — | — | CN | disclosed |
| CN-106674220-A | N-methyl enoxacin aldehyde-4-aryl thiosemicarbazide derivative, and preparation method and application thereof | 郑州工业应用技术学院 | 2017-05-17 | — | — | CN | disclosed |