SCHEMBL28249294

SCHEMBL28249294

Bc1ccc(OCc2ccccc2)c(OC)c1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 3/20 0.57
RAB9A P51151 3/20 0.57
HPGD P15428 2/20 0.57
SMN1; SMN2 Q16637 1/20 0.57
MEN1 O00255 1/20 0.55
KMT2A Q03164 1/20 0.55
KDM4E B2RXH2 2/20 0.53
CYP1A2 P05177 1/20 0.53
CYP3A4 P08684 1/20 0.53
CYP2D6 P10635 1/20 0.53
CYP2C9 P11712 1/20 0.53
BLM P54132 1/20 0.53
ALDH1A1 P00352 3/20 0.53
HSD17B10 Q99714 2/20 0.53
USP2 O75604 1/20 0.53
LMNA P02545 1/20 0.53
TSHR P16473 1/20 0.53
HTR1A P08908 1/20 0.53
ADRA1D P25100 1/20 0.53
ADRA1A P35348 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19831010 0.93 SMPD1 (0.59) NPC1RAB9AHPGDSMN1; SMN2KMT2A
SCHEMBL20807100 0.90 MAPT (0.48) NPC1RAB9AHPGDSMN1; SMN2MEN1
SCHEMBL10176688 0.83 FFAR4 (0.57) SMN1; SMN2CYP2C9HTR1ASMPD1HDAC1
SCHEMBL6881536 0.81 BCHE (0.63) NPC1RAB9AHPGDSMN1; SMN2MEN1
SCHEMBL171847 0.81 NPC1 (0.58) NPC1RAB9AHPGDSMN1; SMN2MEN1
SCHEMBL18623122 0.81 MAOB (0.62) NPC1RAB9AHPGDSMN1; SMN2MEN1
SCHEMBL12772071 0.81 MAOB (0.62) NPC1RAB9AHPGDSMN1; SMN2MEN1
SCHEMBL16369296 0.80 PDGFRB (0.51) NPC1RAB9AHPGDSMN1; SMN2MEN1
SCHEMBL21667956 0.80 FFAR1 (0.58) NPC1RAB9AHPGDSMN1; SMN2MEN1
SCHEMBL6830402 0.80 APP (0.68) NPC1RAB9AHPGDSMN1; SMN2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118239843-A Polymerizable compounds and their use in liquid crystal displays 默克专利股份有限公司 2024-06-25 CN disclosed
CN-117486722-A Polymerizable compounds and their use in liquid crystal displays 默克专利股份有限公司 2024-02-02 CN disclosed
CN-108698973-A Polymerizable compound and use its liquid-crystal composition DIC株式会社 2018-10-23 CN disclosed