SCHEMBL28249807

SCHEMBL28249807

CCCCCCCCC1CCCC1CCCCCCCC

nearest known ligand 0.48

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 3/20 0.48
ALDH1A1 P00352 1/20 0.46
ALOX5 P09917 1/20 0.45
CYP1A2 P05177 3/20 0.42
TSHR P16473 1/20 0.42
THRB P10828 1/20 0.42
S1PR1 P21453 3/20 0.41
S1PR3 Q99500 3/20 0.41
S1PR2 O95136 2/20 0.41
S1PR4 O95977 2/20 0.41
S1PR5 Q9H228 2/20 0.41
CHRNB2 P17787 1/20 0.41
CHRNA7 P36544 1/20 0.41
CHRNA4 P43681 1/20 0.41
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CA4 P22748 1/20 0.39
LSS P48449 2/20 0.36
GBA1 P04062 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28380195 1.00 EPHX1 (0.48) EPHX1ALDH1A1ALOX5CYP1A2TSHR
SCHEMBL29385123 1.00 EPHX1 (0.48) EPHX1ALDH1A1ALOX5CYP1A2TSHR
SCHEMBL29559353 1.00 EPHX1 (0.48) EPHX1ALDH1A1ALOX5CYP1A2TSHR
SCHEMBL8791144 0.97 EPHX1 (0.44) EPHX1ALDH1A1ALOX5CYP1A2TSHR
SCHEMBL29904850 0.95 EPHX1 (0.48) EPHX1ALDH1A1ALOX5CYP1A2TSHR
SCHEMBL29455101 0.95 EPHX1 (0.48) EPHX1ALDH1A1ALOX5CYP1A2TSHR
SCHEMBL4004983 0.95 EPHX1 (0.48) EPHX1ALDH1A1ALOX5CYP1A2TSHR
SCHEMBL29904852 0.95 EPHX1 (0.48) EPHX1ALDH1A1ALOX5CYP1A2TSHR
SCHEMBL28358906 0.95 EPHX1 (0.48) EPHX1ALDH1A1ALOX5CYP1A2TSHR
SCHEMBL28118428 0.95 EPHX1 (0.48) EPHX1ALDH1A1ALOX5CYP1A2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108658762-A A kind of synthetic method of alicyclic ring neighbour diester 浙江凯普化工有限公司 2018-10-16 CN disclosed