Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR3 | Q9UBY5 | 6/20 | 0.55 |
| ▸ | LPAR1 | Q92633 | 4/20 | 0.55 |
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.55 |
| ▸ | BTN3A1 | O00481 | 3/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | MVD | P53602 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL379135 | 0.98 | LPAR3 (0.57) | LPAR3LPAR1LPAR2BTN3A1CYP3A4 | |
| SCHEMBL18798621 | 0.94 | LPAR3 (0.53) | LPAR3LPAR1LPAR2BTN3A1CYP3A4 | |
| SCHEMBL10935345 | 0.94 | LPAR3 (0.53) | LPAR3LPAR1LPAR2BTN3A1CYP3A4 | |
| SCHEMBL2869539 | 0.92 | LPAR3 (0.67) | LPAR3LPAR1LPAR2BTN3A1CYP3A4 | |
| SCHEMBL5705550 | 0.90 | LPAR3 (0.50) | LPAR3LPAR1LPAR2BTN3A1CYP3A4 | |
| SCHEMBL2858464 | 0.90 | LPAR3 (0.70) | LPAR3LPAR1LPAR2BTN3A1CYP3A4 | |
| SCHEMBL2868507 | 0.90 | LPAR3 (0.70) | LPAR3LPAR1LPAR2BTN3A1CYP3A4 | |
| SCHEMBL6253419 | 0.90 | LPAR3 (0.70) | LPAR3LPAR1LPAR2BTN3A1CYP3A4 | |
| SCHEMBL7850798 | 0.90 | LPAR3 (0.70) | LPAR3LPAR1LPAR2BTN3A1CYP3A4 | |
| SCHEMBL2868942 | 0.90 | LPAR3 (0.70) | LPAR3LPAR1LPAR2BTN3A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109661232-A | NUCLEOTIDE DERIVATIVES AND METHODS OF USE THEREOF | 纽约哥伦比亚大学董事会 | 2019-04-19 | — | — | CN | disclosed |
| CN-108779138-A | Design and synthesis of nucleotides based on novel disulfide linkers for use as reversible terminators for DNA sequencing by synthesis | 哥伦比亚大学董事会 | 2018-11-09 | — | — | CN | disclosed |
| CN-104024269-B | 5-methoxy, 3' -OH unblocked, rapidly photocleavable terminating nucleotides and methods for nucleic acid sequencing | 激光基因公司 | 2017-05-24 | — | — | CN | disclosed |