⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL194096 | 0.71 | — | — | |
| SCHEMBL29549708 | 0.71 | — | — | |
| SCHEMBL28252301 | 0.67 | TDP1 (0.34) | — | |
| SCHEMBL29244497 | 0.67 | — | — | |
| SCHEMBL30874762 | 0.67 | — | — | |
| SCHEMBL27014225 | 0.67 | — | — | |
| SCHEMBL31465413 | 0.67 | — | — | |
| SCHEMBL28834352 | 0.67 | — | — | |
| SCHEMBL2936869 | 0.67 | — | — | |
| SCHEMBL1403883 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104955805-B | Inhibitors of syk | 霍夫曼-拉罗奇有限公司 | 2018-11-09 | — | — | CN | disclosed |