2,6-Dimethoxybenzoic Acid

2,6-Dimethoxybenzoic Acid

SCHEMBL28252005

COc1cccc(OC)c1C(=O)O.[NaH]

nearest known ligand 0.95

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.95
CA1 P00915 1/20 0.95
CA2 P00918 1/20 0.95
CA7 P43166 1/20 0.95
CA9 Q16790 1/20 0.95
CA14 Q9ULX7 1/20 0.95
PPARA Q07869 1/20 0.56
HTT P42858 2/20 0.50
FABP4 P15090 1/20 0.49
KDM4E B2RXH2 3/20 0.49
ALDH1A1 P00352 3/20 0.49
HPGD P15428 3/20 0.49
HSD17B10 Q99714 2/20 0.49
TAAR1 Q96RJ0 1/20 0.49
POLB P06746 2/20 0.47
SMN1; SMN2 Q16637 2/20 0.47
MAPT P10636 2/20 0.47
EDNRA P25101 1/20 0.47
MEN1 O00255 1/20 0.47
GAA P10253 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
2,6-Dimethoxybenzoic Acid SCHEMBL149926 0.98 CA12 (1.00) CA12CA1CA2CA7CA9
2,6-Dimethoxybenzoic Acid SCHEMBL10830715 0.95 CA12 (0.95) CA12CA1CA2CA7CA9
2,6-Dimethoxybenzoic Acid SCHEMBL7867072 0.95 CA12 (0.95) CA12CA1CA2CA7CA9
2,6-Dimethoxybenzoic Acid SCHEMBL28906099 0.95 CA12 (0.95) CA12CA1CA2CA7CA9
2,6-Dimethoxybenzoic Acid SCHEMBL11457745 0.95 CA12 (0.95) CA12CA1CA2CA7CA9
SCHEMBL1805910 0.87 CA12 (0.80) CA12CA1CA2CA7CA9
SCHEMBL9394952 0.86 CA12 (0.78) CA12CA1CA2CA7CA9
SCHEMBL29547019 0.85 CA12 (0.77) CA12CA1CA2CA7CA9
SCHEMBL383873 0.85 CA12 (0.77) CA12CA1CA2CA7CA9
SCHEMBL426616 0.85 CA12 (0.77) CA12CA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108779067-A The preparation method of sulfoxide derivant 组合化学工业株式会社 2018-11-09 CN disclosed