⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20494745 | 1.00 | — | — | |
| SCHEMBL6525766 | 0.96 | — | — | |
| SCHEMBL7746177 | 0.79 | — | — | |
| SCHEMBL6523224 | 0.76 | — | — | |
| SCHEMBL282623 | 0.72 | — | — | |
| SCHEMBL61179 | 0.72 | — | — | |
| SCHEMBL14123727 | 0.72 | — | — | |
| SCHEMBL16287197 | 0.70 | — | — | |
| SCHEMBL10990133 | 0.69 | — | — | |
| SCHEMBL10990130 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1343 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117062815-A | VMAT2 inhibitors and methods of use | 纽罗克里生物科学有限公司 | 2023-11-14 | — | — | CN | claimed |
| CN-114797970-B | Ethylene oligomerization modification auxiliary agent and homogeneous catalysis system thereof | 浙江大学 | 2023-07-18 | — | — | CN | claimed |
| EP-4168409-A1 | VMAT2 INHIBITORS AND METHODS OF USE | Neurocrine Biosciences, Inc. (US) | 2023-04-26 | — | — | EP | claimed |
| EP-2890375-B1 | SULFAMOYL-ARYLAMIDES AND THE USE THEREOF AS MEDICAMENTS FOR THE TREATMENT OF HEPATITIS B | JANSSEN SCIENCES IRELAND UNLIMITED CO (IE) | 2021-07-28 | — | — | EP | claimed |
| CN-112154147-A | Substituted phenylthiouracils, their salts and their use as herbicides | 先正达农作物保护股份公司 | 2020-12-29 | — | — | CN | claimed |
| US-20200071326-A1 | TAM KINASE INHIBITORS | SYROS PHARMACEUTICALS INC (US) | 2020-03-05 | — | — | US | claimed |
| US-10295907-B2 | Resist underlayer film-forming composition for lithography containing polymer having acrylamide structure and acrylic acid ester structure | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2019-05-21 | — | — | US | claimed |
| WO-2018191587-A1 | TAM KINASE INHIBITORS | SYROS PHARMACEUTICALS, INC. (US) | 2018-10-18 | — | — | WO | claimed |
| US-10065926-B2 | Use of substituted dihydrooxindolylsulfonamides, or the salts thereof, for increasing the stress tolerance of plants | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-09-04 | — | — | US | claimed |
| CN-107849075-A | A kind of phosphoramidate prodrug of nucleoside analog and its application | 四川海思科制药有限公司 | 2018-03-27 | — | — | CN | claimed |
| EP-1254907-B1 | PYRROLOPYRIDAZINE COMPOUND | SANKYO CO (JP) | 2007-05-09 | — | — | EP | claimed |
| CN-1285593-C | Pyrrolopyridazine compound | SANKYO CO (JP) | 2006-11-22 | — | — | CN | claimed |
| US-6734181-B2 | GASTRIC ACID SECRETORY INHIBITION ACTIVITY, GASTRIC MUCOUS MEMBRANE PROTECTION ACTIVITY; TREATMENT OF ULCERS AND HELICOBACTER PYLORI INFECIONS | SANKYO COMPANY, LIMITED (JP) | 2004-05-11 | — | — | US | claimed |
| US-20040014762-A1 | Pyrrolopyridazine compounds | SANKYO COMPANY, LIMITED (JP) | 2004-01-22 | — | — | US | claimed |
| CN-1422272-A | Pyrrolopyridazine compound | SANKYO CO (JP) | 2003-06-04 | — | — | CN | claimed |
| EP-1254907-A1 | PYRROLOPYRIDAZINE COMPOUND | Sankyo Company, Limited (JP) | 2002-11-06 | — | — | EP | claimed |
| EP-0239357-B1 | PROCESS FOR PREPARING MONOSODIUM PHOSPHOENOLPYRUVATE AND USE OF THE SAME AS VISCERAL FUNCTION IMPROVER | UBE INDUSTRIES, LTD. (JP) | 1991-10-16 | — | — | EP | claimed |
| US-4874882-A | HYDROLYSIS OF MONOSODIUM MONOSUBSTITUTED PHOSPHOENOLPYRUVATE | UBE INDUSTRIES, LTD. (JP) | 1989-10-17 | — | — | US | claimed |
| EP-0239357-A2 | Process for preparing monosodium phosphoenolpyruvate and use of the same as visceral function improver | UBE INDUSTRIES, LTD. (JP) | 1987-09-30 | — | — | EP | claimed |
| US-4152524-A | BRONCHODILATORS, HYPOTENSIVE | AMERICAN CYANAMID COMPANY (US) | 1979-05-01 | — | — | US | claimed |