SCHEMBL28254705

SCHEMBL28254705

CCCCC(Br)c1ccccn1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNA5 P22460 4/20 0.49
KCNH2 Q12809 4/20 0.49
CYP2D6 P10635 4/20 0.46
KCNE1 P15382 1/20 0.46
TSHR P16473 2/20 0.43
SLC6A2 P23975 5/20 0.41
SLC6A4 P31645 5/20 0.41
CHRM2 P08172 4/20 0.41
SCN1A P35498 3/20 0.41
SCN2A Q99250 3/20 0.41
SCN3A Q9NY46 3/20 0.41
CYP1A2 P05177 2/20 0.41
ALDH1A1 P00352 1/20 0.41
SLC6A3 Q01959 4/20 0.40
CHRM1 P11229 3/20 0.40
HRH1 P35367 3/20 0.40
HRH3 Q9Y5N1 3/20 0.40
DRD1 P21728 2/20 0.40
NFKB1 P19838 2/20 0.40
THPO P40225 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29031285 0.95 KCNA5 (0.47) KCNA5KCNH2CYP2D6KCNE1TSHR
SCHEMBL28669183 0.93 KCNA5 (0.46) KCNA5KCNH2CYP2D6KCNE1TSHR
SCHEMBL28347623 0.93 KCNA5 (0.46) KCNA5KCNH2CYP2D6KCNE1TSHR
SCHEMBL21405673 0.93 KCNA5 (0.46) KCNA5KCNH2CYP2D6KCNE1TSHR
Bromide SCHEMBL9168336 0.93 KCNA5 (0.46) KCNA5KCNH2CYP2D6KCNE1TSHR
SCHEMBL28260638 0.93 KCNA5 (0.46) KCNA5KCNH2CYP2D6KCNE1TSHR
SCHEMBL28130837 0.93 KCNA5 (0.46) KCNA5KCNH2CYP2D6KCNE1TSHR
SCHEMBL29145046 0.93 KCNA5 (0.46) KCNA5KCNH2CYP2D6KCNE1TSHR
Water SCHEMBL28366590 0.92 KCNA5 (0.45) KCNA5KCNH2CYP2D6KCNE1TSHR
Ammonia Solution, Strong SCHEMBL28719662 0.92 KCNA5 (0.45) KCNA5KCNH2CYP2D6KCNE1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116946989-A Preparation method of phosphane/deuterated phosphane and derivatives thereof 北京大学 2023-10-27 CN disclosed
CN-108863917-A A kind of preparation method of 2,5- dimethoxy-pyridine 穆云 2018-11-23 CN disclosed