SCHEMBL28255136

SCHEMBL28255136

NC(=O)c1ccc(C(=O)Nc2ccc(N)cc2C(F)(F)F)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.59
CYP2C19 P33261 2/20 0.59
CYP2D6 P10635 1/20 0.59
RAB9A P51151 1/20 0.59
PTGS1 P23219 7/20 0.49
MAPT P10636 4/20 0.48
GAA P10253 1/20 0.48
MAPK1 P28482 1/20 0.48
CYP2C9 P11712 1/20 0.47
HDAC1 Q13547 2/20 0.46
HDAC8 Q9BY41 1/20 0.46
HDAC6 Q9UBN7 1/20 0.46
MEN1 O00255 3/20 0.44
KMT2A Q03164 3/20 0.44
P2RY14 Q15391 2/20 0.44
SMN1; SMN2 Q16637 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
HSD17B10 Q99714 1/20 0.43
LMNA P02545 2/20 0.43
KDM4E B2RXH2 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29996855 0.94 CYP1A2 (0.66) CYP1A2CYP2C19CYP2D6RAB9APTGS1
SCHEMBL26416602 0.94 CYP1A2 (0.66) CYP1A2CYP2C19CYP2D6RAB9APTGS1
SCHEMBL14972697 0.93 CYP1A2 (0.64) CYP1A2CYP2C19CYP2D6RAB9APTGS1
SCHEMBL30319935 0.89 PTGS1 (0.64) CYP1A2CYP2C19CYP2D6RAB9APTGS1
SCHEMBL3528827 0.87 MAPT (0.62) CYP1A2CYP2C19CYP2D6RAB9APTGS1
SCHEMBL26416461 0.86 MAPT (0.66) CYP1A2CYP2C19CYP2D6RAB9APTGS1
SCHEMBL28527141 0.85 CYP1A2 (0.46) CYP1A2CYP2C19CYP2D6RAB9APTGS1
SCHEMBL28895998 0.83 CYP1A2 (0.52) CYP1A2CYP2C19CYP2D6RAB9APTGS1
SCHEMBL28908365 0.81 PTGS1 (0.54) CYP1A2CYP2C19CYP2D6RAB9APTGS1
SCHEMBL30279461 0.81 PTGS1 (0.52) CYP1A2CYP2C19CYP2D6RAB9APTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112500567-B High-modulus transparent polyimide film material containing amide structure and preparation method thereof 奥克控股集团股份公司 2023-03-14 CN claimed
CN-112500567-A High-modulus transparent polyimide film material containing amide structure and preparation method thereof 奥克控股集团股份公司 2021-03-16 CN claimed
CN-112500567-B High-modulus transparent polyimide film material containing amide structure and preparation method thereof 奥克控股集团股份公司 2023-03-14 CN disclosed
CN-115216004-A Polyimide resin, polyimide film, flexible device, and electronic apparatus 华为技术有限公司 2022-10-21 CN disclosed
CN-112500567-A High-modulus transparent polyimide film material containing amide structure and preparation method thereof 奥克控股集团股份公司 2021-03-16 CN disclosed
CN-108864426-B Ultralow-expansion fluorine-containing polyimide film and preparation method and application thereof 中国科学院化学研究所 2020-07-31 CN disclosed
CN-108864426-A A kind of super-low expansion fluorinated polyimide film and the preparation method and application thereof 中国科学院化学研究所 2018-11-23 CN disclosed