SCHEMBL28255437

SCHEMBL28255437

O=C1CSC(c2cc(F)c(F)c(F)c2)N1

nearest known ligand 0.53

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
GFER P55789 1/20 0.49
SMN1; SMN2 Q16637 1/20 0.42
GAA P10253 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28866260 0.84 GFER (0.50) GFERSMN1; SMN2GAAL3MBTL1
SCHEMBL19305941 0.76 GFER (0.54) GFERSMN1; SMN2GAAL3MBTL1
SCHEMBL8099174 0.75 GFER (0.52) GFERSMN1; SMN2GAAL3MBTL1
SCHEMBL9268899 0.73 GFER (0.44) GFERSMN1; SMN2GAAL3MBTL1
SCHEMBL5450446 0.72 SMN1; SMN2 (0.59) GFERSMN1; SMN2GAAL3MBTL1
SCHEMBL9388818 0.70 GFER (0.42) GFERSMN1; SMN2GAAL3MBTL1
SCHEMBL27379404 0.69 SMN1; SMN2 (0.56) GFERSMN1; SMN2GAAL3MBTL1
SCHEMBL27284113 0.69 GFER (0.50) GFERSMN1; SMN2GAAL3MBTL1
SCHEMBL8103620 0.68 GFER (0.49) GFERSMN1; SMN2GAAL3MBTL1
SCHEMBL27420663 0.68 GFER (0.43) GFERSMN1; SMN2GAAL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108883099-A THIAZOLIDINONE COMPOUNDS AND USE THEREOF 石全 2018-11-23 CN disclosed