SCHEMBL28255677

SCHEMBL28255677

COc1ccc(C(=O)OC(C(=O)c2ccc(OC)cc2OC)C(C)CC(C)(C)C)c(OC)c1

nearest known ligand 0.48

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 4/20 0.48
TP53 P04637 1/20 0.47
KMT2A Q03164 5/20 0.46
MEN1 O00255 4/20 0.46
HIF1A Q16665 1/20 0.45
SMN1; SMN2 Q16637 4/20 0.41
LMNA P02545 2/20 0.41
PDE4A P27815 1/20 0.41
PDE4B Q07343 1/20 0.41
PDE4C Q08493 1/20 0.41
PDE4D Q08499 1/20 0.41
HTT P42858 1/20 0.41
RAB9A P51151 3/20 0.41
ALDH1A1 P00352 1/20 0.41
MAPT P10636 1/20 0.41
HPGD P15428 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27614480 0.80 TP53 (0.49) NPC1TP53KMT2AMEN1HIF1A
SCHEMBL28041116 0.79 TP53 (0.48) NPC1TP53KMT2AMEN1HIF1A
SCHEMBL28263413 0.74 TP53 (0.48) NPC1TP53KMT2AMEN1SMN1; SMN2
SCHEMBL14637519 0.74 TP53 (0.48) NPC1TP53KMT2AMEN1SMN1; SMN2
SCHEMBL14519861 0.74 NPC1 (0.60) NPC1TP53KMT2AMEN1HIF1A
SCHEMBL28299179 0.73 CA12 (0.41) KMT2AMEN1SMN1; SMN2ALDH1A1MAPT
SCHEMBL30822790 0.73 KMT2A (0.55) NPC1TP53KMT2AMEN1SMN1; SMN2
SCHEMBL14637515 0.73 TP53 (0.47) NPC1TP53KMT2AMEN1HIF1A
SCHEMBL28279136 0.73 KMT2A (0.60) NPC1TP53KMT2AMEN1SMN1; SMN2
SCHEMBL5993280 0.72 TP53 (0.49) NPC1TP53KMT2AMEN1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110475828-A Ink composition and method for manufacturing organic luminescent device LG CHEMICAL LTD 2019-11-19 CN disclosed
CN-110121493-A Coating composition, organic light emitting diode using the same, and method of manufacturing the same 株式会社LG化学 2019-08-13 CN disclosed
CN-109937243-A Ink composition, organic light-emitting element using same, and method for producing same 株式会社LG化学 2019-06-25 CN disclosed
CN-109863135-A Compound, coating composition comprising the same, organic light emitting device using the same, and method of preparing the same 株式会社LG化学 2019-06-07 CN disclosed
CN-108884042-A Carbazole derivative and organic light-emitting element using same 株式会社LG化学 2018-11-23 CN disclosed