Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 20/20 | 0.82 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2825701 | 0.91 | DHODH (0.68) | DHODH | |
| SCHEMBL468467 | 0.91 | DHODH (1.00) | DHODH | |
| SCHEMBL468583 | 0.90 | DHODH (1.00) | DHODH | |
| SCHEMBL2826408 | 0.89 | DHODH (0.82) | DHODH | |
| SCHEMBL468722 | 0.83 | DHODH (1.00) | DHODH | |
| SCHEMBL2407489 | 0.82 | DHODH (0.82) | DHODH | |
| SCHEMBL468518 | 0.82 | DHODH (1.00) | DHODH | |
| SCHEMBL2822291 | 0.82 | DHODH (0.79) | DHODH | |
| SCHEMBL3665570 | 0.81 | DHODH (0.82) | DHODH | |
| SCHEMBL2826411 | 0.81 | DHODH (0.68) | DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2178840-A1 | AZABIPHENYLAMINOBENZOIC ACID DERIVATIVES AS DHODH INHIBITORS | Almirall, S.A. (ES) | 2010-04-28 | — | — | EP | disclosed |
| WO-2009021696-A1 | AZABIPHENYLAMINOBENZOIC ACID DERIVATIVES AS DHODH INHIBITORS | ALMIRALL, S.A. (ES) | 2009-02-19 | — | — | WO | disclosed |