Urea

Urea

SCHEMBL28257752

FC(F)C(F)(F)C(F)(F)F.NC(N)=O

nearest known ligand 0.35

Full drug profile on Sugi Atlas →

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.35
ALDH1A1 P00352 1/20 0.35
LMNA P02545 1/20 0.35
OR51E2 Q9H255 1/20 0.35
TSHR P16473 2/20 0.34
KDM4E B2RXH2 1/20 0.34
USP2 O75604 1/20 0.32
MAPT P10636 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9651 0.80 KDM4E (0.32) TDP1TSHRKDM4E
SCHEMBL21840732 0.80 KDM4E (0.32) TDP1TSHRKDM4E
SCHEMBL729122 0.80 KDM4E (0.32) TDP1TSHRKDM4E
SCHEMBL2981943 0.80 KDM4E (0.32) TDP1TSHRKDM4E
Acetic Acid SCHEMBL28380342 0.80 FFAR3 (0.39) TDP1TSHRKDM4E
Methyl Alcohol SCHEMBL27678491 0.78 KDM4E (0.33) TDP1TSHRKDM4E
SCHEMBL9160578 0.77 KDM4E (0.31) TDP1TSHRKDM4E
SCHEMBL28353015 0.77 KDM4E (0.31) TDP1TSHRKDM4E
Bromide SCHEMBL30274207 0.77 KDM4E (0.31) TDP1TSHRKDM4E
SCHEMBL28872386 0.77 KDM4E (0.31) TDP1TSHRKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-208181862-U Multi-compartment fire-fighting system of container generator set 泰豪科技股份有限公司 2018-12-04 CN claimed
CN-208181862-U Multi-compartment fire-fighting system of container generator set 泰豪科技股份有限公司 2018-12-04 CN disclosed