Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | BCL2 | P10415 | 1/20 | 0.37 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | SUCNR1 | Q9BXA5 | 3/20 | 0.34 |
| ▸ | SCD | O00767 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | ATR | Q13535 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6058894 | 0.82 | CYP17A1 (0.39) | GRIN2BNAMPTHDAC1BCL2CYP17A1 | |
| SCHEMBL16680158 | 0.82 | NAMPT (0.36) | GRIN2BNAMPTHDAC1BCL2CYP17A1 | |
| SCHEMBL6058970 | 0.80 | GRIN2B (0.38) | GRIN2BNAMPTHDAC1BCL2CYP17A1 | |
| SCHEMBL16296314 | 0.79 | GSK3B (0.41) | GRIN2BNAMPTHDAC1BCL2CYP17A1 | |
| SCHEMBL6059235 | 0.79 | PTGER1 (0.39) | GRIN2BNAMPTHDAC1BCL2CYP17A1 | |
| SCHEMBL24738966 | 0.79 | GSK3B (0.43) | GRIN2BNAMPTHDAC1BCL2CYP17A1 | |
| SCHEMBL30506468 | 0.79 | DEGS1 (0.48) | GRIN2BNAMPTHDAC1BCL2CYP17A1 | |
| SCHEMBL22606745 | 0.79 | DEGS1 (0.48) | GRIN2BNAMPTHDAC1BCL2CYP17A1 | |
| SCHEMBL6058813 | 0.78 | GRIN2B (0.42) | GRIN2BHDAC1BCL2NPSR1SCD | |
| SCHEMBL6058966 | 0.78 | CYP17A1 (0.41) | GRIN2BNAMPTHDAC1BCL2CYP17A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105658646-B | Aminoheteroaryl benzamide as kinase inhibitor | 诺华股份有限公司 | 2018-11-27 | — | — | CN | disclosed |