Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 3/20 | 0.50 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.37 |
| ▸ | MMP3 | P08254 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3965291 | 0.84 | KMT2A (0.44) | ERAP1MAPTKMT2AALDH1A1HPGD | |
| SCHEMBL28259937 | 0.84 | CYSLTR1 (0.43) | ERAP1KMT2AALDH1A1HPGDHSD17B10 | |
| SCHEMBL3967537 | 0.84 | GAA (0.41) | PLK1ERAP1GAAMAPTKMT2A | |
| SCHEMBL3966563 | 0.82 | ESR1 (0.40) | ERAP1ESR1MAPTMAPK10KMT2A | |
| SCHEMBL19437307 | 0.77 | TPMT (0.36) | GAAMAPTKMT2AALDH1A1HPGD | |
| SCHEMBL3966568 | 0.77 | ERAP1 (0.34) | ERAP1GAAMAPTKMT2AHSD17B10 | |
| SCHEMBL19456379 | 0.76 | KDM4E (0.33) | GAAMAPTKMT2AALDH1A1HPGD | |
| SCHEMBL27944839 | 0.73 | PLK1 (0.50) | PLK1GAAMTNR1AALDH1A1HPGD | |
| SCHEMBL7823701 | 0.73 | MEN1 (0.43) | GAAKMT2AALDH1A1HPGDHSD17B10 | |
| SCHEMBL19437420 | 0.72 | KMT2A (0.41) | GAAMAPTKMT2AALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108884083-A | Benzo [ B ] furans as bromodomain inhibitors | 葛兰素史克知识产权第二有限公司 | 2018-11-23 | — | — | CN | disclosed |