SCHEMBL28259082

SCHEMBL28259082

C=C(Br)c1ccc(C(=O)OC(C)(C)C)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 0.50
CA1 P00915 2/20 0.50
CA2 P00918 2/20 0.50
CA9 Q16790 2/20 0.50
CA14 Q9ULX7 2/20 0.50
GABRA1 P14867 1/20 0.41
GABRG2 P18507 1/20 0.41
GABRB3 P28472 1/20 0.41
GABRA3 P34903 1/20 0.41
GABRA2 P47869 1/20 0.41
ELANE P08246 2/20 0.41
TDP1 Q9NUW8 2/20 0.39
ALDH1A1 P00352 1/20 0.39
TSHR P16473 1/20 0.39
HSD17B10 Q99714 1/20 0.39
STAT3 P40763 2/20 0.39
ABCG2 Q9UNQ0 1/20 0.39
SLC7A5 Q01650 1/20 0.37
NOTUM Q6P988 1/20 0.37
ALOX15 P16050 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL109451 0.85 CA1 (0.61) CA12CA1CA2CA9CA14
SCHEMBL9311265 0.82 CA12 (0.51) CA12CA1CA2CA9CA14
Hydrazine SCHEMBL10771056 0.81 CA12 (0.62) CA12CA1CA2CA9CA14
SCHEMBL8567758 0.80 CA12 (0.46) CA12CA1CA2CA9CA14
SCHEMBL277667 0.80 CA1 (0.53) CA12CA1CA2CA9CA14
SCHEMBL97372 0.80 CA12 (0.53) CA12CA1CA2CA9CA14
SCHEMBL7346783 0.80 CA12 (0.53) CA12CA1CA2CA9CA14
SCHEMBL6350965 0.79 CA12 (0.71) CA12CA1CA2CA9CA14
SCHEMBL4532351 0.79 ELANE (0.60) CA12CA1CA2CA9CA14
SCHEMBL4923570 0.79 CA12 (0.49) CA12CA1CA2CA9CA14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106458860-B Pesticidal compositions and methods related thereto 美国陶氏益农公司 2019-07-26 CN disclosed
CN-106165684-B Pesticidal compositions and methods relating thereto 陶氏益农公司 2019-06-14 CN disclosed
CN-105025715-B Pesticidal compositions and methods related thereto 美国陶氏益农公司 2018-11-16 CN disclosed