Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPAS1 | Q99814 | 2/20 | 0.54 |
| ▸ | F10 | P00742 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.45 |
| ▸ | TTR | P02766 | 2/20 | 0.45 |
| ▸ | PPOX | P50336 | 1/20 | 0.45 |
| ▸ | VEGFA | P15692 | 1/20 | 0.45 |
| ▸ | ALB | P02768 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.39 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.39 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.39 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10853274 | 0.91 | EPAS1 (0.55) | EPAS1F10MEN1KMT2ATDP1 | |
| SCHEMBL11740272 | 0.88 | EPAS1 (0.50) | EPAS1F10MEN1KMT2ATDP1 | |
| SCHEMBL11498163 | 0.87 | EPAS1 (0.51) | EPAS1F10MEN1KMT2ATDP1 | |
| SCHEMBL10850140 | 0.85 | EPAS1 (0.49) | EPAS1F10MEN1KMT2ATDP1 | |
| SCHEMBL27343161 | 0.85 | TDP1 (0.65) | EPAS1F10MEN1KMT2ATDP1 | |
| SCHEMBL11056890 | 0.84 | TDP1 (0.53) | EPAS1F10MEN1KMT2ATDP1 | |
| SCHEMBL8772383 | 0.82 | EPAS1 (0.49) | EPAS1F10MEN1KMT2ATDP1 | |
| SCHEMBL6230572 | 0.82 | EPAS1 (0.59) | EPAS1F10MEN1KMT2ATDP1 | |
| SCHEMBL28073333 | 0.80 | KMT2A (0.48) | EPAS1F10MEN1KMT2ATDP1 | |
| SCHEMBL11303611 | 0.80 | TDP1 (0.48) | EPAS1MEN1KMT2ATDP1TTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108997127-A | A kind of production technology synthesizing 1,3- bis--(2- chloro-trifluoromethyl phenoxy) -4- nitrobenzene | 浙江禾本科技有限公司 | 2018-12-14 | — | — | CN | claimed |
| CN-108997127-A | A kind of production technology synthesizing 1,3- bis--(2- chloro-trifluoromethyl phenoxy) -4- nitrobenzene | 浙江禾本科技有限公司 | 2018-12-14 | — | — | CN | disclosed |
| CN-108997127-A | A kind of production technology synthesizing 1,3- bis--(2- chloro-trifluoromethyl phenoxy) -4- nitrobenzene | 浙江禾本科技有限公司 | 2018-12-14 | — | — | CN | disclosed |