Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ACE | P12821 | 10/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4990259 | 0.94 | SMN1; SMN2 (0.48) | SMN1; SMN2LMNAL3MBTL1ALDH1A1POLB | |
| SCHEMBL6656396 | 0.87 | SMN1; SMN2 (0.44) | SMN1; SMN2LMNAL3MBTL1ALDH1A1POLB | |
| Hydrochloric Acid SCHEMBL5593739 | 0.87 | SMN1; SMN2 (0.44) | SMN1; SMN2LMNAL3MBTL1ALDH1A1POLB | |
| SCHEMBL6656395 | 0.87 | SMN1; SMN2 (0.44) | SMN1; SMN2LMNAL3MBTL1ALDH1A1POLB | |
| SCHEMBL8261408 | 0.85 | SMN1; SMN2 (0.50) | SMN1; SMN2LMNAL3MBTL1ALDH1A1POLB | |
| SCHEMBL8971348 | 0.84 | SMN1; SMN2 (0.42) | SMN1; SMN2LMNAL3MBTL1ALDH1A1POLB | |
| SCHEMBL8971352 | 0.84 | SMN1; SMN2 (0.42) | SMN1; SMN2LMNAL3MBTL1ALDH1A1POLB | |
| SCHEMBL10834757 | 0.82 | SMN1; SMN2 (0.50) | SMN1; SMN2LMNAL3MBTL1ALDH1A1POLB | |
| SCHEMBL1994862 | 0.82 | SMN1; SMN2 (0.44) | SMN1; SMN2LMNAL3MBTL1ALDH1A1POLB | |
| SCHEMBL1994865 | 0.82 | SMN1; SMN2 (0.44) | SMN1; SMN2LMNAL3MBTL1ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109021064-A | A kind of preparation method of enalapril maleate | 扬子江药业集团有限公司 | 2018-12-18 | — | — | CN | disclosed |