Benzonitrile

Benzonitrile

SCHEMBL28259455

CC(C)(C)OC=O.N#Cc1ccccc1

nearest known ligand 0.54

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.54
TDP1 Q9NUW8 1/20 0.50
MAOB P27338 3/20 0.38
MAOA P21397 2/20 0.38
CYP1A2 P05177 1/20 0.38
CYP2C19 P33261 1/20 0.38
KIF11 P52732 1/20 0.37
PRSS1 P07477 2/20 0.37
CTSG P08311 2/20 0.37
CTRB1 P17538 2/20 0.37
CMA1 P23946 2/20 0.37
ALDH1A1 P00352 3/20 0.37
MAPT P10636 2/20 0.37
LMNA P02545 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
SLC22A12 Q96S37 1/20 0.36
CYP2A6 P11509 1/20 0.35
KMT2A Q03164 2/20 0.35
NPC1 O15118 1/20 0.35
GAA P10253 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenylacetylene SCHEMBL27853693 0.81 TDP1 (0.50) TSHRTDP1ALDH1A1MAPTNPC1
Benzonitrile SCHEMBL27730371 0.79 TSHR (0.70) TSHRMAOBMAOAALDH1A1MAPT
Benzonitrile SCHEMBL28618826 0.79 TSHR (0.70) TSHRMAOBMAOAALDH1A1MAPT
Benzonitrile SCHEMBL27493881 0.79 TSHR (0.70) TSHRMAOBMAOAALDH1A1MAPT
Tert-Butyl Formate SCHEMBL28106695 0.78 TDP1 (0.81) TSHRTDP1ALDH1A1CYP2A6
Biphenyl SCHEMBL27794837 0.77 TDP1 (0.62) TSHRTDP1CYP1A2CYP2C19KIF11
Tert-Butyl Formate SCHEMBL28266342 0.76 TDP1 (0.77) TSHRTDP1ALDH1A1
Tert-Butyl Formate SCHEMBL28032597 0.75 TDP1 (0.59) TSHRTDP1CYP1A2CYP2C19ALDH1A1
Benzonitrile SCHEMBL27460248 0.74 TSHR (0.70) TSHRMAOBMAOAALDH1A1MAPT
Benzonitrile SCHEMBL16468987 0.74 TSHR (0.78) TSHRMAOBMAOAALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108929285-A The preparation method of Na+ molecular fluorescence intermediate and Na+ molecular fluorescence sensor 苏州首通科技发展有限公司 2018-12-04 CN disclosed