Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.44 |
| ▸ | COPS5 | Q92905 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MITF | O75030 | 1/20 | 0.44 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28261089 | 0.98 | KDM4E (0.46) | KDM4EGAANPC1RAB9APSMD14 | |
| SCHEMBL28259645 | 0.91 | KDM4E (0.41) | KDM4EGAANPC1RAB9APSMD14 | |
| SCHEMBL30114981 | 0.76 | KDM4E (0.49) | KDM4EGAANPC1RAB9APSMD14 | |
| SCHEMBL30114982 | 0.76 | KDM4E (0.49) | KDM4EGAANPC1RAB9APSMD14 | |
| SCHEMBL2161037 | 0.76 | KDM4E (0.52) | KDM4EGAANPC1RAB9APSMD14 | |
| SCHEMBL30114987 | 0.76 | KDM4E (0.49) | KDM4EGAANPC1RAB9APSMD14 | |
| SCHEMBL2161036 | 0.76 | KDM4E (0.52) | KDM4EGAANPC1RAB9APSMD14 | |
| SCHEMBL28485955 | 0.74 | KDM4E (0.56) | KDM4EGAANPC1RAB9AL3MBTL1 | |
| SCHEMBL216372 | 0.73 | KDM4E (0.54) | KDM4EGAANPC1RAB9APSMD14 | |
| SCHEMBL5857429 | 0.70 | KDM4E (0.50) | KDM4EGAANPC1RAB9APSMD14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108948052-A | A kind of N- heterocyclic amino group thiocarbamide mixed-valence copper complex and application thereof | 南通大学 | 2018-12-07 | — | — | CN | disclosed |