Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKACA | P17612 | 1/20 | 0.33 |
| ▸ | PRKACG | P22612 | 1/20 | 0.33 |
| ▸ | PRKACB | P22694 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8024919 | 0.76 | PRKACA (0.30) | PRKACAPRKACGPRKACB | |
| SCHEMBL1847850 | 0.70 | PRKACA (0.48) | PRKACAPRKACGPRKACBBRD4GAA | |
| SCHEMBL3749343 | 0.68 | GAA (0.43) | PRKACAPRKACGPRKACBGAAKMT2A | |
| SCHEMBL28251842 | 0.66 | BRD4 (0.32) | BRD4 | |
| SCHEMBL27388477 | 0.65 | PRKACA (0.31) | PRKACAPRKACGPRKACBBRD4 | |
| SCHEMBL13428861 | 0.64 | PRKACA (0.33) | PRKACAPRKACGPRKACB | |
| SCHEMBL1558012 | 0.64 | — | — | |
| SCHEMBL6683717 | 0.62 | MAPT (0.47) | BRD4GAA | |
| SCHEMBL20819066 | 0.60 | CDK5 (0.56) | PRKACAKMT2A | |
| SCHEMBL27388476 | 0.60 | PRKACA (0.30) | PRKACAPRKACGPRKACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105693612-B | Bridging type arylpyrazole type amide compound and its solvent heat one-pot synthesis method and application | 中南民族大学 | 2019-01-08 | — | — | CN | disclosed |