Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL364719 | 0.89 | — | — | |
| Phosphine SCHEMBL3658909 | 0.89 | — | — | |
| Phosphine SCHEMBL27715025 | 0.89 | — | — | |
| Bromide SCHEMBL29288513 | 0.89 | — | — | |
| Hydrochloric Acid SCHEMBL3660213 | 0.80 | — | — | |
| SCHEMBL49765 | 0.78 | — | — | |
| Bromide SCHEMBL9264026 | 0.68 | — | — | |
| SCHEMBL17491833 | 0.67 | — | — | |
| Fluoride SCHEMBL22265126 | 0.67 | — | — | |
| SCHEMBL10888412 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230066557-A1 | LARGE SCALE PRODUCTION OF CATECHOL-CONTAINING POLYMERS | PURDUE RESEARCH FOUNDATION (US) | 2023-03-02 | — | — | US | disclosed |
| WO-2021127079-A1 | LARGE SCALE PRODUCTION OF CATECHOL-CONTAINING POLYMERS | PURDUE RESEARCH FOUNDATION (US) | 2021-06-24 | — | — | WO | disclosed |
| US-RE47142-E1 | Compounds and methods for treating inflammatory and fibrotic disorders | INTERMUNE, INC. (US) | 2018-11-27 | — | — | US | disclosed |
| US-9356292-B2 | Radical composition and battery using same | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 2016-05-31 | — | — | US | disclosed |
| US-9290450-B2 | Compounds and methods for treating inflammatory and fibrotic disorders | INTERMUNE, INC. (US) | 2016-03-22 | — | — | US | disclosed |
| EP-2296653-B1 | COMPOUNDS AND METHODS FOR TREATING INFLAMMATORY AND FIBROTIC DISORDERS | INTERMUNE INC (US) | 2016-01-27 | — | — | EP | disclosed |
| US-8969347-B2 | Compounds and methods for treating inflammatory and fibrotic disorders | INTERMUNE, INC. | 2015-03-03 | — | — | US | disclosed |
| US-20140235637-A1 | COMPOUNDS AND METHODS FOR TREATING INFLAMMATORY AND FIBROTIC DISORDERS | INTERMUNE, INC. (US) | 2014-08-21 | — | — | US | disclosed |
| US-20140061532-A1 | RADICAL COMPOSITION AND BATTERY USING SAME | WASEDA UNIVERSITY (JP) | 2014-03-06 | — | — | US | disclosed |
| US-8501805-B2 | Substituted alpha-L-bicyclic nucleosides | ISIS PHARMACEUTICALS, INC. (US) | 2013-08-06 | — | — | US | disclosed |
| US-6296978-B1 | LIGHT SENSITIVE ELEMENTS FOR IMAGES | CANON KABUSHIKI KAISHA (JP) | 2001-10-02 | — | — | US | disclosed |
| EP-0686636-B1 | TRICYCLIC BENZAZEPINE AND BENZOTHIAZEPINE DERIVATIVES | MEIJI SEIKA CO (JP) | 2001-04-04 | — | — | EP | disclosed |
| EP-0885054-A1 | THE USE OF AN EARLIER KNOWN SEPARATION MATERIAL AND NOVEL FORMS OF THE MATERIAL | Amersham Pharmacia Biotech AB (SE) | 1998-12-23 | — | — | EP | disclosed |
| US-5840895-A | INTERMEDIATES FOR ANTIALLERGENS | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1998-11-24 | — | — | US | disclosed |
| EP-0875791-A2 | An electrophotographic photosensitive member, a process-cartridge inclusive thereof, and an image forming apparatus | CANON KABUSHIKI KAISHA (JP) | 1998-11-04 | — | — | EP | disclosed |
| US-5686442-A | ANTIALLERGENS | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1997-11-11 | — | — | US | disclosed |
| WO-1997026071-A1 | THE USE OF AN EARLIER KNOWN SEPARATION MATERIAL AND NOVEL FORMS OF THE MATERIAL | AMERSHAM PHARMACIA BIOTECH AB (SE) | 1997-07-24 | — | — | WO | disclosed |
| EP-0686636-A1 | TRICYCLIC BENZAZEPINE AND BENZOTHIAZEPINE DERIVATIVES | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1995-12-13 | — | — | EP | disclosed |
| EP-0637297-A4 | COMPOUNDS HAVING SELECTIVITY FOR RETINOID X RECEPTORS. | LIGAND PHARM INC (US) | 1995-09-20 | — | — | EP | disclosed |
| WO-1994013691-A1 | THIO- AND OXO-AZASTEROIDS, PROCESSES FOR THE PREPARATION THEREOF, USE THEREOF AS ANTIANDROGENS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | POLI INDUSTRIA CHIMICA S.P.A. (IT) | 1994-06-23 | — | — | WO | disclosed |