Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 6/20 | 0.61 |
| ▸ | CTSG | P08311 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 5/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | USP2 | O75604 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | RECQL | P46063 | 3/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | MAOA | P21397 | 2/20 | 0.44 |
| ▸ | APEX1 | P27695 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | RAF1 | P04049 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14680732 | 0.80 | ELANE (0.72) | ELANECTSGMEN1MAPTKMT2A | |
| SCHEMBL29359549 | 0.78 | ELANE (0.70) | ELANECTSGMEN1MAPTKMT2A | |
| SCHEMBL30432375 | 0.78 | ELANE (0.70) | ELANECTSGMEN1MAPTKMT2A | |
| SCHEMBL10909836 | 0.78 | ELANE (0.70) | ELANECTSGMEN1MAPTKMT2A | |
| SCHEMBL17689250 | 0.77 | MEN1 (0.79) | ELANECTSGMEN1MAPTKMT2A | |
| SCHEMBL6152288 | 0.76 | NQO1 (0.52) | ELANECTSGMEN1MAPTKMT2A | |
| SCHEMBL1426900 | 0.76 | ELANE (1.00) | ELANECTSGMEN1MAPTKMT2A | |
| SCHEMBL31298578 | 0.76 | ELANE (1.00) | ELANECTSGMEN1MAPTKMT2A | |
| SCHEMBL19461991 | 0.76 | ELANE (1.00) | ELANECTSGMEN1MAPTKMT2A | |
| SCHEMBL13894735 | 0.74 | ELANE (0.54) | ELANECTSGMEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112574033-B | Synthesis method of 1-hydroxy-2,5,8-trimethyl-9-fluorenone | 江西中医药大学 | 2023-08-04 | — | — | CN | claimed |
| CN-112574033-A | Synthesis method of 1-hydroxy-2,5,8-trimethyl-9-fluorenone | 江西中医药大学 | 2021-03-30 | — | — | CN | claimed |
| CN-112574033-B | Synthesis method of 1-hydroxy-2,5,8-trimethyl-9-fluorenone | 江西中医药大学 | 2023-08-04 | — | — | CN | disclosed |
| CN-112574033-B | Synthesis method of 1-hydroxy-2,5,8-trimethyl-9-fluorenone | 江西中医药大学 | 2023-08-04 | — | — | CN | disclosed |
| CN-112574033-B | Synthesis method of 1-hydroxy-2,5,8-trimethyl-9-fluorenone | 江西中医药大学 | 2023-08-04 | — | — | CN | disclosed |
| CN-109020797-B | Preparation method and application of two thermal decomposition products of tripterine | 江西中医药大学 | 2021-04-06 | — | — | CN | disclosed |
| CN-112574033-A | Synthesis method of 1-hydroxy-2,5,8-trimethyl-9-fluorenone | 江西中医药大学 | 2021-03-30 | — | — | CN | disclosed |
| CN-112574033-A | Synthesis method of 1-hydroxy-2,5,8-trimethyl-9-fluorenone | 江西中医药大学 | 2021-03-30 | — | — | CN | disclosed |
| CN-112574033-A | Synthesis method of 1-hydroxy-2,5,8-trimethyl-9-fluorenone | 江西中医药大学 | 2021-03-30 | — | — | CN | disclosed |
| CN-109020797-A | The preparation method and applications of two kinds of thermal decomposition products of Celastrol | 江西中医药大学 | 2018-12-18 | — | — | CN | disclosed |