⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19207518 | 0.86 | — | — | |
| SCHEMBL22609451 | 0.63 | — | — | |
| SCHEMBL9129871 | 0.62 | — | — | |
| SCHEMBL1826731 | 0.62 | — | — | |
| SCHEMBL768641 | 0.59 | — | — | |
| SCHEMBL8040938 | 0.59 | — | — | |
| SCHEMBL12548595 | 0.57 | — | — | |
| SCHEMBL2387121 | 0.55 | — | — | |
| SCHEMBL17309004 | 0.55 | — | — | |
| SCHEMBL11171567 | 0.55 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114206861-A | Fused heteroaryl compounds useful as RIPK1 inhibitors | 比西切姆有限公司 | 2022-03-18 | — | — | CN | disclosed |
| CN-109071504-A | Inhibitors of receptor interacting protein kinase 1 | 戴纳立制药公司 | 2018-12-21 | — | — | CN | disclosed |