Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 18/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 6/20 | 0.43 |
| ▸ | PIK3R1 | P27986 | 2/20 | 0.43 |
| ▸ | PIK3C3 | Q8NEB9 | 2/20 | 0.41 |
| ▸ | RICTOR | Q6R327 | 2/20 | 0.41 |
| ▸ | RPTOR | Q8N122 | 2/20 | 0.41 |
| ▸ | MAPKAP1 | Q9BPZ7 | 2/20 | 0.41 |
| ▸ | MLST8 | Q9BVC4 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27833947 | 0.83 | MTOR (0.51) | MTORPIK3CAPIK3R1 | |
| SCHEMBL2528288 | 0.81 | MTOR (0.45) | MTORPIK3CAPIK3R1PIK3C3RICTOR | |
| SCHEMBL20606347 | 0.80 | MTOR (0.46) | MTORPIK3CAPIK3R1RICTORRPTOR | |
| SCHEMBL30933171 | 0.80 | MTOR (0.52) | MTORPIK3CAPIK3R1PIK3C3RICTOR | |
| SCHEMBL20605988 | 0.80 | MTOR (0.46) | MTORPIK3CAPIK3R1RICTORRPTOR | |
| SCHEMBL24756512 | 0.80 | MTOR (0.52) | MTORPIK3CAPIK3R1PIK3C3RICTOR | |
| SCHEMBL20605987 | 0.80 | MTOR (0.46) | MTORPIK3CAPIK3R1RICTORRPTOR | |
| SCHEMBL4776072 | 0.78 | PIK3CD (0.44) | MTORPIK3CA | |
| SCHEMBL26151682 | 0.78 | MTOR (0.47) | MTORPIK3CAPIK3R1RICTORRPTOR | |
| SCHEMBL20605955 | 0.76 | MTOR (0.44) | MTORPIK3CAPIK3R1RICTORRPTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109195965-A | The inhibitor that WDR5 protein-protein combines | 普罗佩纶治疗公司 | 2019-01-11 | — | — | CN | disclosed |