⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL380648 | 0.59 | — | — | |
| SCHEMBL410711 | 0.57 | — | — | |
| SCHEMBL77749 | 0.49 | — | — | |
| SCHEMBL93164 | 0.46 | — | — | |
| SCHEMBL719234 | 0.39 | — | — | |
| SCHEMBL12992748 | 0.37 | — | — | |
| SCHEMBL102954 | 0.37 | — | — | |
| SCHEMBL4070 | 0.37 | — | — | |
| SCHEMBL1203 | 0.37 | — | — | |
| SCHEMBL34570 | 0.37 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 80988 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240228501-A1 | IMIDAZOLE-CONTAINING CONDENSED RING DERIVATIVE, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF IN MEDICINE | CHANGCHUN GENESCIENCE PHARMACEUTICAL CO., LTD. (CN) | 2024-07-11 | — | — | US | claimed |
| CN-118265786-A | Microtubule-associated protein Tau (MAPT) iRNA pharmaceutical compositions and methods of use thereof | 阿尔尼拉姆医药品有限公司 | 2024-06-28 | — | — | CN | claimed |
| WO-2024131776-A1 | BUFALIN DERIVATIVE AND PREPARATION METHOD THEREFOR, COMPOSITION, PREPARATION, AND APPLICATION | 上海邈基生物科技有限公司 | 2024-06-27 | — | — | WO | claimed |
| US-20240209373-A1 | ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN 1 (ELOVL1) iRNA AGENT COMPOSITIONS AND METHODS OF USE THEREOF | ALNYLAM PHARMACEUTICALS, INC. (US) | 2024-06-27 | — | — | US | claimed |
| US-20240209374-A1 | iRNA COMPOSITIONS AND METHODS FOR SILENCING CHITINASE 3-LIKE PROTEIN 1/YKL-40 (CHI3L1/YKL-40) PROTEIN | ALNYLAM PHARMACEUTICALS, INC. (US) | 2024-06-27 | — | — | US | claimed |
| US-20240199603-A1 | HPK1 ANTAGONISTS AND USES THEREOF | SCHRÖDINGER, INC. | 2024-06-20 | — | — | US | claimed |
| US-20240200077-A1 | STEAROYL-COA DESATURASE 5 (SCD5) IRNA AGENT COMPOSITIONS AND METHODS OF USE THEREOF | ALNYLAM PHARMACEUTICALS, INC. (US) | 2024-06-20 | — | — | US | claimed |
| EP-4380565-A1 | HPK1 ANTAGONISTS AND USES THEREOF | Nimbus Saturn, Inc. (US) | 2024-06-12 | — | — | EP | claimed |
| CN-118176300-A | Huntington (HTT) iRNA agent compositions and methods of use thereof | 阿尔尼拉姆医药品有限公司 | 2024-06-11 | — | — | CN | claimed |
| WO-2024109798-A1 | LIPID COMPOUND AND LIPID NANOPARTICLE COMPOSITION | 苏州艾博生物科技有限公司 | 2024-05-30 | — | — | WO | claimed |
| US-4247550-A | Compositions and methods for the treatment of hypertension or oedemas | LEO PHARMACEUTICAL PRODUCTS LTD. A/S (LOVENS KEMISKE FABRIK PRODUKTIONSAKTIESELSKAB) (DK) | 1981-01-27 | — | — | US | claimed |
| EP-0021173-A1 | Maytansinoids, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1981-01-07 | — | — | EP | claimed |
| US-4213898-A | FOR POLYACRYLONITRILE | SANDOZ LTD. (CH) | 1980-07-22 | — | — | US | claimed |
| EP-0005379-A2 | Photosensitive compositions containing carbonylic halides as activators | Dynachem Corporation (US) | 1979-11-14 | — | — | EP | claimed |
| EP-0005380-A2 | Phototropic photosensitive compositions containing a fluoran colorformer | Dynachem Corporation (US) | 1979-11-14 | — | — | EP | claimed |
| US-4153460-A | Light-sensitive silver halide color photographic material | KONISHIROKU PHOTO INDUSTRY CO., LTD (JP) | 1979-05-08 | — | — | US | claimed |
| US-4113867-A | ANTHELMINTICS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1978-09-12 | — | — | US | claimed |
| US-3998803-A | TEXTILES | FIDELITY UNION TRUST COMPANY, EXECUTIVE TRUSTEE UNDER THE SANDOZ TRUST (US) | 1976-12-21 | — | — | US | claimed |
| US-3997519-A | Method of producing quaternary pyridinium compounds | GAF CORPORATION (US) | 1976-12-14 | — | — | US | claimed |
| US-3979455-A | Preparation of dioxyimino-cycloalkanones and related intermediates | TEXACO INC. (US) | 1976-09-07 | — | — | US | claimed |