SCHEMBL28271964

SCHEMBL28271964

COC(=O)CCNC(=O)[C@H](O)C(C)(C)CO.[NaH]

nearest known ligand 0.61

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 1/20 0.61
KCNH2 Q12809 1/20 0.61
VNN1 O95497 13/20 0.55
TSHR P16473 2/20 0.38
CA12 O43570 1/20 0.37
CA14 Q9ULX7 1/20 0.37
EPHX2 P34913 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7524751 0.98 PTGS1 (0.63) PTGS1KCNH2VNN1TSHRCA12
SCHEMBL10932748 0.98 PTGS1 (0.63) PTGS1KCNH2VNN1TSHRCA12
SCHEMBL7524756 0.98 PTGS1 (0.63) PTGS1KCNH2VNN1TSHRCA12
SCHEMBL11750108 0.97 PTGS1 (0.61) PTGS1KCNH2VNN1TSHRCA12
Water SCHEMBL29206580 0.97 PTGS1 (0.61) PTGS1KCNH2VNN1TSHRCA12
SCHEMBL10774486 0.90 PTGS1 (0.61) PTGS1KCNH2VNN1
SCHEMBL7016637 0.89 PTGS1 (0.63) PTGS1KCNH2VNN1
SCHEMBL2458620 0.87 PTGS1 (0.61) PTGS1KCNH2VNN1
SCHEMBL27597358 0.87 PTGS1 (0.61) PTGS1KCNH2VNN1
SCHEMBL888201 0.87 PTGS1 (0.61) PTGS1KCNH2VNN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109280015-A A kind of synthesis of D-VB5 sodium and chiral separation method 无锡凯夫制药有限公司 2019-01-29 CN disclosed