Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Monoethanolamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydroxyamine SCHEMBL27914147 | 0.84 | — | — | |
| Propylamine SCHEMBL29070629 | 0.83 | HSP90AA1 (0.33) | HSP90AA1 | |
| Alcohol SCHEMBL28114729 | 0.83 | — | — | |
| Hydrazine SCHEMBL28115277 | 0.82 | — | — | |
| SCHEMBL80643 | 0.82 | — | — | |
| Fluoride SCHEMBL27461973 | 0.82 | — | — | |
| SCHEMBL969300 | 0.82 | — | — | |
| SCHEMBL4198 | 0.82 | — | — | |
| SCHEMBL4621927 | 0.82 | FABP6 (0.35) | ALDH1A1TSHRHSP90AA1 | |
| Urea SCHEMBL6097799 | 0.80 | HSP90AA1 (0.33) | HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109320492-A | The method for preparing homopiperony lamine hydrochloride and berberine | 湖北文理学院 | 2019-02-12 | — | — | CN | disclosed |