SCHEMBL2827573

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL13395462	0.91	PTK2 (0.84)	PTK2MAPK10MAPK9MAPK8CDC7
	SCHEMBL2825624	0.89	PTK2 (1.00)	PTK2MAPK10MAPK9MAPK8CDC7
	SCHEMBL13395466	0.84	POLB (0.63)	PTK2MAPK8EGFRINSRIGF1R
	SCHEMBL14503208	0.83	MAPT (0.69)	PTK2MAPK8INSRMAPK1LRRK2
	SCHEMBL24377553	0.83	PTK2 (1.00)	PTK2MAPK10MAPK9MAPK8CDC7
	SCHEMBL29378728	0.83	PTK2 (1.00)	PTK2MAPK10MAPK9MAPK8CDC7
	SCHEMBL19654204	0.83	PTK2 (0.85)	PTK2MAPK10MAPK9MAPK8CDC7
	SCHEMBL375524	0.83	PTK2 (1.00)	PTK2MAPK10MAPK9MAPK8CDC7
	SCHEMBL29730430	0.83	PTK2 (1.00)	PTK2MAPK10MAPK9MAPK8CDC7
	SCHEMBL12627645	0.82	PTK2 (0.84)	PTK2MAPK10MAPK9MAPK8CDC7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.