Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.33 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.32 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.32 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.32 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.32 |
| ▸ | RARA | P10276 | 1/20 | 0.32 |
| ▸ | RARB | P10826 | 1/20 | 0.32 |
| ▸ | RARG | P13631 | 1/20 | 0.32 |
| ▸ | LDHA | P00338 | 1/20 | 0.31 |
| ▸ | RORC | P51449 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28349555 | 0.88 | SETD7 (0.40) | NPC1RAB9AEGFRKDM4ESMN1; SMN2 | |
| SCHEMBL29163406 | 0.85 | NPC1 (0.38) | NPC1RAB9AEGFRMKNK1MKNK2 | |
| SCHEMBL483513 | 0.84 | NPC1 (0.47) | NPC1RAB9AEGFRMKNK1MKNK2 | |
| SCHEMBL25395879 | 0.84 | NPC1 (0.47) | NPC1RAB9AEGFRMKNK1MKNK2 | |
| SCHEMBL25394857 | 0.84 | NPC1 (0.47) | NPC1RAB9AEGFRMKNK1MKNK2 | |
| SCHEMBL29163495 | 0.84 | NPC1 (0.37) | NPC1RAB9AEGFRMKNK1MKNK2 | |
| SCHEMBL28232546 | 0.81 | NPC1 (0.34) | NPC1RAB9AEGFRMKNK1MKNK2 | |
| SCHEMBL3475755 | 0.80 | TSHR (0.44) | NPC1RAB9AMKNK1MKNK2KDM4E | |
| SCHEMBL28089246 | 0.80 | BCL2L1 (0.33) | NPC1RAB9AMKNK1MKNK2KDM4E | |
| SCHEMBL17183610 | 0.79 | TP53 (0.43) | NPC1RAB9AMKNK1MKNK2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118021991-A | Acid response self-assembled nanomaterial capable of targeting mitochondria and application thereof in preparation of antitumor drugs | 哈尔滨医科大学 | 2024-05-14 | — | — | CN | claimed |
| CN-114225054-B | Application of hybrid organic-metal framework magnetic material as nuclear magnetic resonance contrast agent | 中国科学院宁波材料技术与工程研究所慈溪生物医学工程研究所 | 2024-04-12 | — | — | CN | claimed |
| CN-117304516-A | Low-temperature adaptive in-situ hydrogel and preparation method and application thereof | 广西大学 | 2023-12-29 | — | — | CN | claimed |
| CN-114230803-A | Metal organic framework composite nano material and preparation method and application thereof | 中国科学院宁波材料技术与工程研究所慈溪生物医学工程研究所 | 2022-03-25 | — | — | CN | claimed |
| CN-114225054-A | Application of hybrid organic-metal framework magnetic material as nuclear magnetic resonance contrast agent | 中国科学院宁波材料技术与工程研究所慈溪生物医学工程研究所 | 2022-03-25 | — | — | CN | claimed |
| CN-112871216-B | CO2Bismuth-based MOFs photocatalyst for cycloaddition reaction and preparation method and application thereof | 山东大学 | 2022-03-04 | — | — | CN | claimed |
| CN-110845740-B | Cyclodextrin metal framework circular polarization luminescent crystal and preparation method and application thereof | 中国科学院化学研究所 | 2022-02-08 | — | — | CN | claimed |
| CN-112871216-A | CO2Bismuth-based MOFs photocatalyst for cycloaddition reaction and preparation method and application thereof | 山东大学 | 2021-06-01 | — | — | CN | claimed |
| CN-112535660-A | Three-level targeted pH sensitive type nano drug-loaded micelle and preparation method and application thereof | 上海交通大学医学院附属第九人民医院 | 2021-03-23 | — | — | CN | claimed |
| CN-110845740-A | Cyclodextrin metal framework circular polarization luminescent crystal and preparation method and application thereof | 中国科学院化学研究所 | 2020-02-28 | — | — | CN | claimed |
| CN-109394691-A | A kind of multistage pH sensitivity nano medicament carrying system | 青岛大学 | 2019-03-01 | — | — | CN | claimed |
| CN-118021991-A | Acid response self-assembled nanomaterial capable of targeting mitochondria and application thereof in preparation of antitumor drugs | 哈尔滨医科大学 | 2024-05-14 | — | — | CN | disclosed |
| CN-114225054-B | Application of hybrid organic-metal framework magnetic material as nuclear magnetic resonance contrast agent | 中国科学院宁波材料技术与工程研究所慈溪生物医学工程研究所 | 2024-04-12 | — | — | CN | disclosed |
| CN-115399328-B | Polysaccharide-based sterilization material and preparation method and application thereof | 中国科学院化学研究所 | 2024-03-22 | — | — | CN | disclosed |
| CN-117304516-A | Low-temperature adaptive in-situ hydrogel and preparation method and application thereof | 广西大学 | 2023-12-29 | — | — | CN | disclosed |
| CN-110845740-B | Cyclodextrin metal framework circular polarization luminescent crystal and preparation method and application thereof | 中国科学院化学研究所 | 2022-02-08 | — | — | CN | disclosed |
| CN-112871216-A | CO2Bismuth-based MOFs photocatalyst for cycloaddition reaction and preparation method and application thereof | 山东大学 | 2021-06-01 | — | — | CN | disclosed |
| CN-112535660-A | Three-level targeted pH sensitive type nano drug-loaded micelle and preparation method and application thereof | 上海交通大学医学院附属第九人民医院 | 2021-03-23 | — | — | CN | disclosed |
| CN-110845740-A | Cyclodextrin metal framework circular polarization luminescent crystal and preparation method and application thereof | 中国科学院化学研究所 | 2020-02-28 | — | — | CN | disclosed |
| CN-109394691-A | A kind of multistage pH sensitivity nano medicament carrying system | 青岛大学 | 2019-03-01 | — | — | CN | disclosed |