SCHEMBL28279341

SCHEMBL28279341

COc1ccc(C(=O)CC(C)CC(=O)c2ccc(OC)cc2OC)c(OC)c1

nearest known ligand 0.59

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.58
TP53 P04637 1/20 0.58
LMNA P02545 1/20 0.58
HTT P42858 1/20 0.58
RAB9A P51151 5/20 0.57
NPC1 O15118 4/20 0.57
PKM P14618 1/20 0.55
MEN1 O00255 1/20 0.54
KMT2A Q03164 1/20 0.54
L3MBTL1 Q9Y468 2/20 0.52
MAPT P10636 2/20 0.52
USP2 O75604 1/20 0.52
CASP3 P42574 1/20 0.52
SENP8 Q96LD8 1/20 0.52
SENP7 Q9BQF6 1/20 0.52
SENP6 Q9GZR1 1/20 0.52
TDP1 Q9NUW8 1/20 0.52
ALDH1A1 P00352 1/20 0.51
ABCG2 Q9UNQ0 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27982705 0.90 TP53 (0.62) SMN1; SMN2TP53LMNAHTTRAB9A
Hydrochloric Acid SCHEMBL28047706 0.89 TP53 (0.61) SMN1; SMN2TP53LMNAHTTRAB9A
SCHEMBL27857159 0.88 SMN1; SMN2 (0.56) SMN1; SMN2TP53LMNAHTTRAB9A
SCHEMBL2978070 0.83 SMN1; SMN2 (0.65) SMN1; SMN2TP53LMNAHTTRAB9A
SCHEMBL194153 0.82 SMN1; SMN2 (0.53) SMN1; SMN2TP53LMNAHTTRAB9A
SCHEMBL29816340 0.82 SMN1; SMN2 (0.53) SMN1; SMN2TP53LMNAHTTRAB9A
SCHEMBL1172826 0.81 SMN1; SMN2 (0.63) SMN1; SMN2TP53LMNAHTTRAB9A
SCHEMBL4653380 0.81 SMN1; SMN2 (0.63) SMN1; SMN2TP53LMNAHTTRAB9A
SCHEMBL5914630 0.81 SMN1; SMN2 (0.63) SMN1; SMN2TP53LMNAHTTRAB9A
SCHEMBL30376093 0.81 SMN1; SMN2 (0.63) SMN1; SMN2TP53LMNAHTTRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109313299-A Polarizing film with double-sided adhesive layer and image display device 日东电工株式会社 2019-02-05 CN disclosed