Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.53 |
| ▸ | CA2 | P00918 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.47 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.47 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Guaiacol SCHEMBL4092047 | 0.82 | CA1 (0.56) | CA1CA2TP53TSHRMAOB | |
| Naphthalene SCHEMBL28174978 | 0.81 | GAA (0.50) | TSHRKMT2AMEN1SMN1; SMN2ALDH1A1 | |
| Guaiacol SCHEMBL27262484 | 0.81 | CA1 (0.69) | CA1CA2TP53TSHRMAOB | |
| Guaiacol SCHEMBL27644634 | 0.80 | TSHR (0.62) | CA1CA2TP53TSHRMAOB | |
| Guaiacol SCHEMBL27728369 | 0.77 | CA1 (0.58) | CA1CA2TP53TSHRMAOB | |
| Benzene SCHEMBL28198430 | 0.77 | MGAM (0.48) | TSHRKMT2AMEN1LMNASMN1; SMN2 | |
| Guaiacol SCHEMBL28300008 | 0.76 | TP53 (0.62) | CA1CA2TP53TSHRMAOB | |
| Guaiacol SCHEMBL5323161 | 0.76 | TP53 (0.62) | CA1CA2TP53TSHRMAOB | |
| Guaiacol SCHEMBL15532049 | 0.75 | CA1 (0.78) | CA1CA2TP53TSHRMAOB | |
| Guaiacol SCHEMBL27881624 | 0.75 | CA1 (0.78) | CA1CA2TP53TSHRMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109369591-A | A kind of synthetic method of diosmetin | 陕西嘉禾生物科技股份有限公司 | 2019-02-22 | — | — | CN | disclosed |