Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX4 | Q99571 | 9/20 | 0.43 |
| ▸ | CFD | P00746 | 1/20 | 0.41 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28279246 | 0.93 | P2RX4 (0.47) | P2RX4CFDCYP2C8CYP2D6CYP2C9 | |
| SCHEMBL29716961 | 0.93 | MEN1 (0.47) | P2RX4CYP2C8CYP2D6CYP2C9ADRA2B | |
| SCHEMBL19551528 | 0.93 | MEN1 (0.47) | P2RX4CYP2C8CYP2D6CYP2C9ADRA2B | |
| SCHEMBL19551571 | 0.90 | P2RX4 (0.52) | P2RX4CYP2C8CYP2D6CYP2C9ADRA2B | |
| SCHEMBL19551591 | 0.90 | P2RX4 (0.53) | P2RX4CYP2C8CYP2D6CYP2C9ADRA2B | |
| SCHEMBL29716850 | 0.90 | P2RX4 (0.53) | P2RX4CYP2C8CYP2D6CYP2C9ADRA2B | |
| SCHEMBL28280337 | 0.89 | P2RX4 (0.46) | P2RX4CFDCYP2C8CYP2D6CYP2C9 | |
| SCHEMBL28279232 | 0.89 | P2RX4 (0.47) | P2RX4CFDCYP2C8CYP2D6CYP2C9 | |
| SCHEMBL19551561 | 0.88 | CA12 (0.54) | P2RX4CA12CA1CA2CA9 | |
| SCHEMBL19551548 | 0.88 | CA1 (0.43) | P2RX4CYP2C8CYP2D6CYP2C9ADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109415321-A | aromatic sulfonamide derivatives | 拜耳制药股份公司 | 2019-03-01 | — | — | CN | disclosed |