Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.51 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | GLS | O94925 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | NOS1 | P29475 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | PLG | P00747 | 1/20 | 0.40 |
| ▸ | PLAU | P00749 | 1/20 | 0.40 |
| ▸ | CDC7 | O00311 | 1/20 | 0.40 |
| ▸ | PTPRC | P08575 | 1/20 | 0.39 |
| ▸ | S100A4 | P26447 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5150336 | 0.86 | CDC7 (0.49) | SLC6A2MAPTCYP1A2TSHRLMNA | |
| SCHEMBL28142780 | 0.79 | SLC6A2 (0.51) | SLC6A2CYP19A1GLSMAPTCYP1A2 | |
| SCHEMBL1098394 | 0.79 | CYP19A1 (0.51) | SLC6A2CYP19A1GLSMAPTCYP1A2 | |
| SCHEMBL28030880 | 0.79 | SLC6A2 (0.51) | SLC6A2CYP19A1GLSMAPTCYP1A2 | |
| SCHEMBL3224421 | 0.79 | SLC6A2 (0.51) | SLC6A2CYP19A1GLSMAPTCYP1A2 | |
| SCHEMBL3218015 | 0.79 | SLC6A2 (0.51) | SLC6A2CYP19A1GLSMAPTCYP1A2 | |
| SCHEMBL30078606 | 0.78 | SLC6A2 (0.48) | SLC6A2CYP19A1GLSMAPTCYP1A2 | |
| SCHEMBL257518 | 0.76 | SLC6A2 (0.49) | SLC6A2CYP19A1GLSMAPTCYP1A2 | |
| SCHEMBL28910295 | 0.76 | SLC6A2 (0.49) | SLC6A2CYP19A1GLSMAPTCYP1A2 | |
| SCHEMBL2420811 | 0.75 | CYP1A2 (0.53) | SLC6A2CYP19A1GLSMAPTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117843548-A | Benzyl indole HDAC inhibitor and pharmaceutical application thereof | 南京医科大学 | 2024-04-09 | — | — | CN | disclosed |
| CN-104870422-B | Amine derivative or its salt | 富士胶片富山化学株式会社 | 2019-03-15 | — | — | CN | disclosed |