Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR3 | Q9UBY5 | 9/20 | 0.55 |
| ▸ | LPAR2 | Q9HBW0 | 6/20 | 0.55 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | CDC25A | P30304 | 1/20 | 0.44 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.44 |
| ▸ | AKT1 | P31749 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | TRPM8 | Q7Z2W7 | 5/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27845147 | 1.00 | LPAR3 (0.55) | LPAR3LPAR2LPAR1CYP3A4LMNA | |
| SCHEMBL1295944 | 1.00 | LPAR3 (0.55) | LPAR3LPAR2LPAR1CYP3A4LMNA | |
| SCHEMBL27973262 | 0.98 | LPAR3 (0.53) | LPAR3LPAR2LPAR1CYP3A4LMNA | |
| SCHEMBL27845160 | 0.96 | CYP3A4 (0.52) | LPAR3LPAR2LPAR1CYP3A4TRPM8 | |
| SCHEMBL27973437 | 0.94 | CYP3A4 (0.50) | LPAR3LPAR2LPAR1CYP3A4TRPM8 | |
| SCHEMBL28225458 | 0.92 | LPAR3 (0.45) | LPAR3LPAR2LPAR1CYP3A4TRPM8 | |
| SCHEMBL11833546 | 0.91 | LPAR3 (0.59) | LPAR3LPAR2LPAR1CYP3A4LMNA | |
| SCHEMBL941506 | 0.91 | LPAR3 (0.59) | LPAR3LPAR2LPAR1CYP3A4LMNA | |
| SCHEMBL9757468 | 0.91 | LPAR3 (0.59) | LPAR3LPAR2LPAR1CYP3A4LMNA | |
| SCHEMBL11835424 | 0.91 | LPAR3 (0.59) | LPAR3LPAR2LPAR1CYP3A4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109415470-A | Liquid composition comprising a phosphorus-based additive, use thereof and material or composition obtained after polymerization of the composition | 阿肯马法国公司 | 2019-03-01 | — | — | CN | disclosed |