Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | KHK | P50053 | 2/20 | 0.45 |
| ▸ | BCL2A1 | Q16548 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | KIT | P10721 | 1/20 | 0.37 |
| ▸ | CDK1 | P06493 | 3/20 | 0.36 |
| ▸ | CDK4 | P11802 | 3/20 | 0.36 |
| ▸ | CCNA2 | P20248 | 3/20 | 0.36 |
| ▸ | CCND3 | P30281 | 3/20 | 0.36 |
| ▸ | CDK6 | Q00534 | 3/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31084546 | 1.00 | MAPT (0.46) | MAPTKHKBCL2A1ALDH1A1LMNA | |
| SCHEMBL20159005 | 0.86 | MAPT (0.49) | MAPTKHKBCL2A1ALDH1A1LMNA | |
| SCHEMBL8110875 | 0.86 | MAPT (0.49) | MAPTKHKBCL2A1ALDH1A1LMNA | |
| SCHEMBL20158997 | 0.84 | KHK (0.49) | MAPTKHKBCL2A1ALDH1A1LMNA | |
| SCHEMBL8108460 | 0.82 | BCL2A1 (0.55) | MAPTKHKBCL2A1ALDH1A1LMNA | |
| SCHEMBL8106618 | 0.81 | KHK (0.49) | MAPTKHKBCL2A1ALDH1A1LMNA | |
| SCHEMBL2245477 | 0.80 | TLR9 (0.47) | MAPTKHKBCL2A1TLR9TLR8 | |
| SCHEMBL5270098 | 0.80 | TLR9 (0.47) | MAPTKHKBCL2A1TLR9TLR8 | |
| SCHEMBL27660899 | 0.80 | MAPT (0.44) | MAPTKHKBCL2A1ALDH1A1LMNA | |
| SCHEMBL18825829 | 0.80 | MAPT (0.42) | MAPTKHKBCL2A1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105829315-B | Pyrimidopyrimidinones useful as Wee-1 kinase inhibitors | 阿尔麦克探索有限公司 | 2019-03-08 | — | — | CN | disclosed |