SCHEMBL28284530

SCHEMBL28284530

C1CC2OC2O1.CC(=O)OC(C)(C)C

nearest known ligand 0.32

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
RECQL P46063 1/20 0.32
USP2 O75604 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
CHRM2 P08172 1/20 0.30
CHRM1 P11229 1/20 0.30
CHRM3 P20309 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28864982 0.76 RECQL (0.35) RECQLUSP2SMN1; SMN2CHRM2CHRM1
Fluoride SCHEMBL28312813 0.72
SCHEMBL1429860 0.72
Dioxane SCHEMBL28175114 0.71 SMN1; SMN2 (0.55) RECQLUSP2SMN1; SMN2
Methylamine SCHEMBL28787480 0.70 GAA (0.46) USP2SMN1; SMN2CHRM2CHRM1CHRM3
SCHEMBL28358909 0.69 GAA (0.50) USP2SMN1; SMN2CHRM2CHRM1CHRM3
SCHEMBL28342310 0.69 GAA (0.50) USP2SMN1; SMN2CHRM2CHRM1CHRM3
SCHEMBL28745990 0.69 GAA (0.50) USP2SMN1; SMN2CHRM2CHRM1CHRM3
SCHEMBL26684 0.69
Cyclopropane SCHEMBL28162716 0.68 GAA (0.44) USP2SMN1; SMN2CHRM2CHRM1CHRM3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109574938-A A kind of synthetic method of Rosuvastatin sodium 安徽省庆云医药股份有限公司 2019-04-05 CN disclosed
CN-109574999-A A kind of preparation method of Pitavastatin Calcium intermediate 安徽省庆云医药股份有限公司 2019-04-05 CN disclosed
CN-109574939-A A kind of preparation method of Rosuvastatin sodium 安徽省庆云医药股份有限公司 2019-04-05 CN disclosed