SCHEMBL28286189

SCHEMBL28286189

CCCCC(C#N)(C(=O)OCC)C(CC)C(=O)OCC

nearest known ligand 0.41

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
MAPT P10636 1/20 0.36
ATM Q13315 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
CYP4F2 P78329 2/20 0.33
CYP4A11 Q02928 2/20 0.33
ALDH1A1 P00352 1/20 0.33
TSHR P16473 1/20 0.33
THRB P10828 1/20 0.33
PKM P14618 1/20 0.33
HTT P42858 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28286195 0.96 MEN1 (0.41) MEN1KMT2AMAPTATML3MBTL1
SCHEMBL28284641 0.94 MEN1 (0.43) MEN1KMT2AMAPTATML3MBTL1
SCHEMBL28870969 0.91 MEN1 (0.42) MEN1KMT2AMAPTATML3MBTL1
SCHEMBL23142369 0.90 MEN1 (0.43) MEN1KMT2AMAPTATML3MBTL1
SCHEMBL21313382 0.90 MEN1 (0.40) MEN1KMT2AMAPTATML3MBTL1
SCHEMBL29072604 0.89 MEN1 (0.39) MEN1KMT2ACYP4F2CYP4A11ALDH1A1
SCHEMBL23142360 0.89 MEN1 (0.39) MEN1KMT2AMAPTATML3MBTL1
SCHEMBL23142400 0.87 MEN1 (0.38) MEN1KMT2AMAPTATML3MBTL1
SCHEMBL28312993 0.87 MEN1 (0.40) MEN1KMT2AMAPTATML3MBTL1
SCHEMBL23142368 0.86 MEN1 (0.37) MEN1KMT2AMAPTATML3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117924549-A Ziegler-Natta catalyst component, process for preparing the same, olefin polymerization catalyst and process for polymerizing olefin 中国石油化工股份有限公司 2024-04-26 CN disclosed
CN-116769096-A Preparation method of high isotactic polybutene-1 中国石油化工股份有限公司 2023-09-19 CN disclosed
CN-116769078-A Catalyst component for olefin polymerization and application thereof 中国石油化工股份有限公司 2023-09-19 CN disclosed
CN-116769091-A Preparation method of polybutene-1 resin 中国石油化工股份有限公司 2023-09-19 CN disclosed
CN-106608937-B Catalytic component and its preparation method and application for olefinic polymerization 中国石油化工股份有限公司 2019-04-19 CN disclosed
CN-106608933-B Catalytic component and its preparation method and application for olefinic polymerization 中国石油化工股份有限公司 2019-03-26 CN disclosed