SCHEMBL2828736

SCHEMBL2828736

CCOc1cc(C(=O)O)c(OCC)cc1C(=O)O

nearest known ligand 0.75

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.75
HSD17B10 Q99714 2/20 0.75
CYP3A4 P08684 1/20 0.64
KDM4E B2RXH2 4/20 0.55
LMNA P02545 2/20 0.51
TP53 P04637 2/20 0.50
LCK P06239 1/20 0.48
FYN P06241 1/20 0.48
KMT2A Q03164 1/20 0.48
L3MBTL1 Q9Y468 2/20 0.47
GLA P06280 1/20 0.47
RXRA P19793 1/20 0.46
HNF4A P41235 1/20 0.46
ALDH1A1 P00352 2/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
CYP1A2 P05177 1/20 0.46
HPGD P15428 1/20 0.46
RCE1 Q9Y256 1/20 0.46
GAA P10253 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18309198 0.92 TSHR (0.66) TSHRHSD17B10CYP3A4KDM4ELMNA
SCHEMBL22067760 0.90 TSHR (0.64) TSHRHSD17B10CYP3A4KDM4ELMNA
SCHEMBL11777279 0.89 TSHR (0.62) TSHRHSD17B10CYP3A4KDM4ELMNA
SCHEMBL11232189 0.86 TSHR (0.59) TSHRHSD17B10CYP3A4KDM4ELMNA
SCHEMBL7802436 0.86 TSHR (0.76) TSHRHSD17B10CYP3A4KDM4ELMNA
SCHEMBL19873258 0.86 TSHR (1.00) TSHRHSD17B10CYP3A4KDM4ELMNA
SCHEMBL1107710 0.85 KDM4E (0.63) TSHRHSD17B10CYP3A4KDM4ELMNA
SCHEMBL868527 0.83 KDM4E (0.67) TSHRHSD17B10KDM4ELMNATP53
SCHEMBL4584625 0.83 TSHR (0.60) TSHRHSD17B10CYP3A4KDM4ELMNA
SCHEMBL1729057 0.83 TSHR (0.65) TSHRHSD17B10CYP3A4KDM4ELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230001379-A1 POLYCRYSTALLINE METAL-ORGANIC FRAMEWORK MEMBRANES FOR SEPARATION OF MIXTURES NATIONAL UNIVERSITY OF SINGAPORE (SG) 2023-01-05 US claimed
CN-114585432-A Polycrystalline metal-organic framework membranes for separating mixtures 新加坡国立大学 2022-06-03 CN claimed
WO-2021066742-A1 POLYCRYSTALLINE METAL-ORGANIC FRAMEWORK MEMBRANES FOR SEPARATION OF MIXTURES NATIONAL UNIVERSITY OF SINGAPORE (SG) 2021-04-08 WO claimed
CN-110227418-A It is a kind of for being enriched with the magnetic COF-TbTpa and its preparation method and application of Fipronil and its metabolin 浙江省农业科学院 2019-09-13 CN claimed
CN-102584873-B Double rare earth metal-organic framework material for temperature detection and synthesis method thereof UNIV ZHEJIANG 2015-07-15 CN claimed
CN-102584873-A Double rare earth metal-organic framework material for temperature detection and synthesis method thereof UNIV ZHEJIANG 2012-07-18 CN claimed
WO-2026100858-A1 POLYMER FILM COMPRISING POLYMER NANOFIBERS LOADED WITH METAL-ORGANIC FRAMEWORKS, TRIBOELECTRIC-BASED NANOGENERATOR COMPRISING SAME, AND METHOD FOR MANUFACTURING POLYMER NANOFIBERS LOADED WITH METAL-ORGANIC FRAMEWORKS 서울대학교산학협력단 2026-05-15 WO disclosed
US-12429387-B2 Photoexcitation-free temperature sensing material, preparation method and temperature sensing method XIAMEN UNIVERSITY (CN) 2025-09-30 US disclosed
US-20230204437-A1 PHOTOEXCITATION-FREE TEMPERATURE SENSING MATERIAL, PREPARATION METHOD AND TEMPERATURE SENSING METHOD XIAMEN UNIVERSITY (CN) 2023-06-29 US disclosed
US-20230001379-A1 POLYCRYSTALLINE METAL-ORGANIC FRAMEWORK MEMBRANES FOR SEPARATION OF MIXTURES NATIONAL UNIVERSITY OF SINGAPORE (SG) 2023-01-05 US disclosed
WO-2022165996-A1 LIGHT-FREE EXCITATION TYPE TEMPERATURE SENSING MATERIAL, PREPARATION METHOD, AND TEMPERATURE SENSING METHOD 厦门大学 2022-08-11 WO disclosed
CN-114585432-A Polycrystalline metal-organic framework membranes for separating mixtures 新加坡国立大学 2022-06-03 CN disclosed
CN-112877061-B Light excitation-free temperature sensing material, preparation method and temperature sensing method 厦门大学 2022-04-29 CN disclosed
CN-102584873-B Double rare earth metal-organic framework material for temperature detection and synthesis method thereof UNIV ZHEJIANG 2015-07-15 CN disclosed
US-8269029-B2 Water repellent metal-organic frameworks, process for making and uses regarding same THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2012-09-18 US disclosed
CN-102584873-A Double rare earth metal-organic framework material for temperature detection and synthesis method thereof UNIV ZHEJIANG 2012-07-18 CN disclosed
CN-102584873-A Double rare earth metal-organic framework material for temperature detection and synthesis method thereof UNIV ZHEJIANG 2012-07-18 CN disclosed
CN-102249901-A Preparation method of 2, 5-dialkoxy terephthalic acid SHANDONG NON METALLIC MATERIAL RES INST 2011-11-23 CN disclosed
CN-102211996-A Preparation method of 2, 5-dihydroxy terephthalic acid SHANDONG NON METALLIC MATERIAL RES INST 2011-10-12 CN disclosed
US-20100075123-A1 WATER REPELLENT METAL-ORGANIC FRAMEWORKS, PROCESS FOR MAKING AND USES REGARDING SAME University of Illinois - Office of Technology Management (US) 2010-03-25 US disclosed