Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | CYP17A1 | P05093 | 6/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28244361 | 0.98 | KDM4E (0.40) | KDM4ECYP26A1CYP19A1KMT2ACYP17A1 | |
| Acetic Acid SCHEMBL27936824 | 0.89 | KDM4E (0.47) | KDM4ECYP26A1KMT2ACYP17A1 | |
| Bromide SCHEMBL29132745 | 0.79 | CYP17A1 (0.38) | CYP19A1CYP17A1 | |
| SCHEMBL5455751 | 0.79 | CYP19A1 (0.40) | CYP19A1CYP17A1 | |
| Bromide SCHEMBL28038388 | 0.78 | CYP17A1 (0.40) | CYP19A1KMT2ACYP17A1 | |
| SCHEMBL19416814 | 0.78 | KDM4E (0.39) | KDM4ECYP26A1CYP19A1KMT2ACYP17A1 | |
| SCHEMBL17742983 | 0.76 | CYP17A1 (0.39) | CYP19A1CYP17A1 | |
| Bromide SCHEMBL25395862 | 0.76 | CYP17A1 (0.44) | KDM4ECYP19A1KMT2ACYP17A1 | |
| SCHEMBL6268997 | 0.76 | — | — | |
| Bromide SCHEMBL28301180 | 0.76 | CYP17A1 (0.40) | CYP19A1CYP17A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109513039-B | Antibacterial hydrogel dressing containing imidazole bromide salt and preparation method and application thereof | 大连工业大学 | 2021-05-14 | — | — | CN | disclosed |
| CN-107219279-B | Nanometer Copper/graphene modified electrode ginsenoside Rg1's molecular engram sensor | 济南大学 | 2019-04-19 | — | — | CN | disclosed |