Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QPCT | Q16769 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.33 |
| ▸ | SCN1A | P35498 | 1/20 | 0.33 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.33 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.33 |
| ▸ | HRH2 | P25021 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10034550 | 1.00 | QPCT (0.35) | QPCTHTR2CHRH3SCN1ASCN2A | |
| SCHEMBL15108634 | 1.00 | QPCT (0.35) | QPCTHTR2CHRH3SCN1ASCN2A | |
| SCHEMBL15217037 | 0.95 | QPCT (0.34) | QPCTHTR2CHRH3MEN1KMT2A | |
| SCHEMBL15217038 | 0.95 | QPCT (0.34) | QPCTHTR2CHRH3MEN1KMT2A | |
| SCHEMBL25112162 | 0.89 | GBA1 (0.37) | QPCTHTR2CMEN1KMT2A | |
| SCHEMBL27230179 | 0.89 | GBA1 (0.37) | QPCTHTR2CMEN1KMT2A | |
| SCHEMBL29323071 | 0.89 | GBA1 (0.37) | QPCTHTR2CMEN1KMT2A | |
| Tert-Butyl Formate SCHEMBL28290454 | 0.85 | TDP1 (0.33) | QPCTHTR2CHRH3SCN1ASCN2A | |
| SCHEMBL3106518 | 0.80 | TAAR1 (0.38) | MEN1KMT2A | |
| SCHEMBL28831368 | 0.79 | MEN1 (0.35) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109563092-B | 2-phenylimidazo [4,5-B ] pyridin-7-amine derivatives useful as inhibitors of the activity of the mammalian tyrosine kinase ROR1 | 坎塞拉有限公司 | 2021-09-14 | — | — | CN | disclosed |
| CN-109563092-A | It can be used as the 2- phenylimidazole of the active inhibitor of mammal tyrosine kinase ROR1 simultaneously [4,5-B] pyridine -7- amine derivative | 坎塞拉有限公司 | 2019-04-02 | — | — | CN | disclosed |