Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNJ1 | P48048 | 20/20 | 0.70 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.70 |
| ▸ | ACHE | P22303 | 1/20 | 0.70 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.70 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20574345 | 0.87 | KCNJ1 (0.71) | KCNJ1KCNH2ACHESSTR1SLC6A4 | |
| SCHEMBL15760962 | 0.87 | KCNJ1 (0.71) | KCNJ1KCNH2ACHESSTR1SLC6A4 | |
| SCHEMBL20167986 | 0.87 | KCNJ1 (0.71) | KCNJ1KCNH2ACHESSTR1SLC6A4 | |
| SCHEMBL20177155 | 0.87 | KCNJ1 (0.71) | KCNJ1KCNH2ACHESSTR1SLC6A4 | |
| SCHEMBL16438855 | 0.86 | KCNJ1 (0.78) | KCNJ1KCNH2ACHESSTR1SLC6A4 | |
| SCHEMBL16869147 | 0.86 | KCNJ1 (0.78) | KCNJ1KCNH2ACHESSTR1SLC6A4 | |
| SCHEMBL20168619 | 0.83 | KCNJ1 (0.67) | KCNJ1KCNH2ACHESSTR1SLC6A4 | |
| Mk-7145 SCHEMBL29778244 | 0.82 | KCNJ1 (1.00) | KCNJ1KCNH2ACHESSTR1SLC6A4 | |
| Mk-7145 SCHEMBL297586 | 0.82 | KCNJ1 (1.00) | KCNJ1KCNH2ACHESSTR1SLC6A4 | |
| Mk-7145 SCHEMBL2894681 | 0.82 | KCNJ1 (1.00) | KCNJ1KCNH2ACHESSTR1SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106432214-B | A method of preparing ROMK channel inhibitor intermediate | 成都拿盛科技有限公司 | 2019-05-07 | — | — | CN | disclosed |