Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4145433 | 0.88 | HTT (0.66) | HTTKDM4ESMN1; SMN2ALDH1A1PDE4B | |
| SCHEMBL16884088 | 0.86 | HTT (0.76) | HTTKDM4ESMN1; SMN2ALDH1A1PDE4B | |
| SCHEMBL3377384 | 0.86 | KDM4E (0.64) | KDM4ETDP1SMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL5755240 | 0.83 | HTT (0.67) | HTTSMN1; SMN2ALDH1A1PDE4BKMT2A | |
| SCHEMBL519845 | 0.82 | HTT (0.70) | HTTSMN1; SMN2ALDH1A1PDE4BKMT2A | |
| SCHEMBL17994023 | 0.82 | KDM4E (0.60) | HTTKDM4ETDP1SMN1; SMN2ALDH1A1 | |
| SCHEMBL24127978 | 0.80 | HRH3 (0.54) | HTTKDM4ESMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL10899727 | 0.80 | GAA (0.71) | HTTKDM4ETDP1SMN1; SMN2ALDH1A1 | |
| SCHEMBL15330913 | 0.80 | HTT (0.62) | HTTSMN1; SMN2ALDH1A1PDE4BKMT2A | |
| SCHEMBL31525420 | 0.80 | HTT (0.66) | HTTSMN1; SMN2ALDH1A1PDE4BKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109678815-A | N- benzyl benzamide derivatives and preparation method thereof and pharmaceutical applications | 中国药科大学 | 2019-04-26 | — | — | CN | disclosed |