Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | TNKS | O95271 | 7/20 | 0.49 |
| ▸ | NPC1 | O15118 | 5/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | PARP1 | P09874 | 4/20 | 0.49 |
| ▸ | TNKS2 | Q9H2K2 | 4/20 | 0.49 |
| ▸ | GABRP | O00591 | 2/20 | 0.49 |
| ▸ | GABRD | O14764 | 2/20 | 0.49 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.49 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.49 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.49 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11646827 | 0.79 | KDM4E (0.51) | HPGDKDM4ELMNAHSD17B10SMN1; SMN2 | |
| SCHEMBL11388353 | 0.78 | KDM4E (0.63) | HPGDKDM4ELMNAHSD17B10SMN1; SMN2 | |
| SCHEMBL27904021 | 0.77 | CYP2A6 (0.53) | HPGDKDM4ELMNAHSD17B10SMN1; SMN2 | |
| SCHEMBL28291744 | 0.76 | TNKS (0.53) | HPGDKDM4ELMNAHSD17B10SMN1; SMN2 | |
| SCHEMBL12325324 | 0.73 | KDM4E (0.66) | HPGDKDM4ELMNAHSD17B10SMN1; SMN2 | |
| SCHEMBL11398949 | 0.73 | KDM4E (0.62) | HPGDKDM4ELMNAHSD17B10SMN1; SMN2 | |
| SCHEMBL3844010 | 0.73 | NPC1 (0.65) | HPGDKDM4ELMNAHSD17B10SMN1; SMN2 | |
| SCHEMBL11388357 | 0.72 | KDM4E (0.60) | HPGDKDM4ELMNAHSD17B10SMN1; SMN2 | |
| SCHEMBL11645674 | 0.72 | KDM4E (0.65) | HPGDKDM4ELMNAHSD17B10SMN1; SMN2 | |
| SCHEMBL11856459 | 0.71 | KDM4E (0.59) | HPGDKDM4ELMNAHSD17B10SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115536644-B | Application of chromone-2-formamide compound in preparation of hypoglycemic drugs and preparation method thereof | 广西民族大学 | 2024-09-03 | — | — | CN | claimed |
| CN-115536644-A | Application of chromone-2-formamide compound in preparation of hypoglycemic drugs and preparation method thereof | 广西民族大学 | 2022-12-30 | — | — | CN | claimed |
| CN-115536644-B | Application of chromone-2-formamide compound in preparation of hypoglycemic drugs and preparation method thereof | 广西民族大学 | 2024-09-03 | — | — | CN | disclosed |
| CN-115536644-B | Application of chromone-2-formamide compound in preparation of hypoglycemic drugs and preparation method thereof | 广西民族大学 | 2024-09-03 | — | — | CN | disclosed |
| CN-115536644-B | Application of chromone-2-formamide compound in preparation of hypoglycemic drugs and preparation method thereof | 广西民族大学 | 2024-09-03 | — | — | CN | disclosed |
| CN-115536644-A | Application of chromone-2-formamide compound in preparation of hypoglycemic drugs and preparation method thereof | 广西民族大学 | 2022-12-30 | — | — | CN | disclosed |
| CN-115536644-A | Application of chromone-2-formamide compound in preparation of hypoglycemic drugs and preparation method thereof | 广西民族大学 | 2022-12-30 | — | — | CN | disclosed |
| CN-115536644-A | Application of chromone-2-formamide compound in preparation of hypoglycemic drugs and preparation method thereof | 广西民族大学 | 2022-12-30 | — | — | CN | disclosed |
| CN-109641864-A | ANTI-INFECTIVE AGENTS | 邓迪大学 | 2019-04-16 | — | — | CN | disclosed |